Evidence map›Paper›PMID 28367103›Full record

ArticleInternational journal of biological sciences2017

Novel approaches to vitiligo treatment via modulation of mTOR and NF-κB pathways in human skin melanocytes.

Jerry Wan, Fuquan Lin, Wei Zhang, Aie Xu, Joseph DeGiorgis, Hongguang Lu, Yinsheng Wan

Open access · goldAbstract read
In one paragraph

Article in International journal of biological sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 36 citations in OpenAlex.

  1. The Role ofInternational journal of molecular sciences · 2026
    Article
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  3. Article
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  5. Article
  6. Review
  7. Article
  8. Review
  9. Vitiligo, from Pathogenesis to Therapeutic Advances: State of the Art.International journal of molecular sciences · 2023
    Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Recent Advances in Management of Vitiligo.Indian journal of dermatology
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jerry WanDepartment of Biology, Providence College, Providence, RI 02918, USA.
Fuquan LinDepartment of Dermatology, the 3 rd Hospital of Hangzhou, Hangzhou 310000, Zhejiang Province, China.
Wei ZhangDepartment of Dermatology, Guiyang Medical University, Guizhou 550004, China.
Aie XuDepartment of Dermatology, the 3 rd Hospital of Hangzhou, Hangzhou 310000, Zhejiang Province, China.
Joseph DeGiorgisDepartment of Biology, Providence College, Providence, RI 02918, USA.
Hongguang LuDepartment of Dermatology, Guiyang Medical University, Guizhou 550004, China.
Yinsheng WanDepartment of Biology, Providence College, Providence, RI 02918, USA.
Providence College · US

Funding

UNDERGRADUATE RESEARCH AND SEMINARSP20RR016457 · NCRR · UNIVERSITY OF RHODE ISLAND · PI MARSTON, MARCIA · 2001 to 2011
$35.5M
NCRR NIH HHS P20 RR016457
6 · The paper itself

Abstract

Vitiligo is a skin depigmentation disorder with an increasing prevalence. Among recognized mechanisms is the oxidative stress that affects melanocytes which are responsible for skin pigmentation. Studies have shown that high concentration of hydrogen peroxide, or H

Indexed as

alpha-MSHBlotting, WesternCells, CulturedChromonesHumansHydrogen PeroxideMelanocytesMicroscopy, ConfocalMorpholinesNF-kappa BPhosphatidylinositol 3-KinasesPhosphoinositide-3 Kinase InhibitorsSirolimusTOR Serine-Threonine KinasesTumor Necrosis Factor-alphaVitiligo2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-onealpha-MSHChromonesHydrogen PeroxideMorpholinesNF-kappa BPhosphatidylinositol 3-KinasesPhosphoinositide-3 Kinase InhibitorsSirolimusTOR Serine-Threonine KinasesTumor Necrosis Factor-alphamTORC1TNFαvitiligoα-MSH

Identifiers

PMID28367103
PMCPMC5370446
OpenAlexW2593742627

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.