Evidence map›Paper›PMID 28367056›Full record

ArticleNeuropsychiatric disease and treatment2017

Association study of

Naofumi Shimmyo, Akitoyo Hishimoto, Ikuo Otsuka, Satoshi Okazaki, Shuken Boku, Kentaro Mouri, Tadasu Horai, Motonori Takahashi, Yasuhiro Ueno, Osamu Shirakawa and 1 more

Open access · goldAbstract read
In one paragraph

Article in Neuropsychiatric disease and treatment, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Article
  7. Association ofInternational journal of clinical and experimental pathology · 2021
    Article
  8. Investigating the Relationship Between DNA Methylation, Genetic Variation, and Suicide Attempt in Bipolar Disorder.Archives of suicide research : official journal of the International Academy for Suicide Research
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Naofumi ShimmyoDepartment of Psychiatry, Department of Community Medicine and Social Health Science, Kobe University Graduate School of Medicine, Kobe.
Akitoyo HishimotoDepartment of Psychiatry, Department of Community Medicine and Social Health Science, Kobe University Graduate School of Medicine, Kobe.
Ikuo OtsukaDepartment of Psychiatry, Department of Community Medicine and Social Health Science, Kobe University Graduate School of Medicine, Kobe.
Satoshi OkazakiDepartment of Psychiatry, Department of Community Medicine and Social Health Science, Kobe University Graduate School of Medicine, Kobe.
Shuken BokuDepartment of Psychiatry, Department of Community Medicine and Social Health Science, Kobe University Graduate School of Medicine, Kobe.
Kentaro MouriDepartment of Psychiatry, Department of Community Medicine and Social Health Science, Kobe University Graduate School of Medicine, Kobe.
Tadasu HoraiDepartment of Psychiatry, Department of Community Medicine and Social Health Science, Kobe University Graduate School of Medicine, Kobe.
Motonori TakahashiDivision of Legal Medicine, Department of Community Medicine and Social Health Science, Kobe University Graduate School of Medicine, Kobe.
Yasuhiro UenoDivision of Legal Medicine, Department of Community Medicine and Social Health Science, Kobe University Graduate School of Medicine, Kobe.
Osamu ShirakawaDepartment of Neuropsychiatry, Kindai University Faculty of Medicine, Osaka, Japan.
Ichiro SoraDepartment of Psychiatry, Department of Community Medicine and Social Health Science, Kobe University Graduate School of Medicine, Kobe.
Kobe University · JPKindai University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNumerous studies suggest that inflammation plays a key role in suicidal behavior. Macrophage migration inhibitory factor (MIF), a proinflammatory cytokine, has received increasing attention in depression research. However, no study has investigated whether

methodsThe subjects comprised 602 suicide completers and 728 healthy controls. We genotyped

resultsAnalyses of allele or genotype frequency distributions of the polymorphisms studied here did not reveal any significant differences between the suicide completers and the controls. Haplotype analysis also revealed no association with completed suicide.

conclusionTo our knowledge, this is the first study that has examined the genetic association between MIF and completed suicide. Our results suggest that the effects of

Indexed as

haplotypemicrosatelliteMIFpromoter regionSNPsuicide

Identifiers

PMID28367056
PMCPMC5370383
OpenAlexW2599713443

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.