Evidence map›Paper›PMID 28366988›Full record

ArticleJournal of clinical biochemistry and nutrition2017

The association of enzymatic and non-enzymatic antioxidant defense parameters with inflammatory markers in patients with exudative form of age-related macular degeneration.

Emina Čolak, Svetlana Ignjatović, Aleksandra Radosavljević, Lepša Žorić

Abstract read
In one paragraph

Article in Journal of clinical biochemistry and nutrition, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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  10. DNA Damage Response and Oxidative Stress in Systemic Autoimmunity.International journal of molecular sciences · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Emina ČolakInstitute of Medical Biochemistry, Clinical Center of Serbia, School of Pharmacy, University of Belgrade, Belgrade 11000, Serbia.
Svetlana IgnjatovićInstitute of Medical Biochemistry, Clinical Center of Serbia, School of Pharmacy, University of Belgrade, Belgrade 11000, Serbia.
Aleksandra RadosavljevićInstitute of Ophthalmology, Medical Retina Department, Clinical Center of Serbia, School of Medicine, University of Belgrade, Belgrade 11000, Serbia.
Lepša ŽorićClinic for Eye Diseases, Clinical Center, Faculty of Medicine, Settlement Kosovska Mitrovica, Kosovska Mitrovica 38200, Serbia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There are evidence that oxidative stress and inflammation are involved in the pathogenesis of the age-related macular degeneration (AMD). The aim of this study was to analyze the antioxidant defense parameters and inflammatory markers in patients with exudative form of AMD (eAMD), their mutual correlations and association with the specific forms of AMD. The cross-sectional study, included 75 patients with the eAMD, 31 patients with the early form, and 87 aged-matched control subjects. Significantly lower SOD, TAS and albumin values and higher GR, CRP and IL-6 were found in the eAMD compared to the early form (

Indexed as

age-related macular degenerationantioxidantsinflammationoxidative stress

Identifiers

PMID28366988
PMCPMC5371514

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.