Evidence map›Paper›PMID 28366932›Full record

ReviewImmunology and cell biology2017

Intravital microscopy in historic and contemporary immunology.

Judith Secklehner, Cristina Lo Celso, Leo M Carlin

Abstract readReview
In one paragraph

Review in Immunology and cell biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Leukocyte Trafficking in Lymphatic Vessels.Cold Spring Harbor perspectives in medicine · 2022
    Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Neutrophil dynamics in the tumor microenvironment.The Journal of clinical investigation · 2021
    Review
  16. Method for Acute Intravital Imaging of the Large Intestine in Live Mice.Methods in molecular biology (Clifton, N.J.) · 2021
    Article
  17. Label-Free Multimodal Multiphoton Intravital Imaging.Advances in experimental medicine and biology · 2021
    Article
  18. Live Imaging.Current issues in molecular biology · 2021
    Review
  19. Actually Seeing What Is Going on - Intravital Microscopy in Tissue Engineering.Frontiers in bioengineering and biotechnology · 2021
    Review
  20. Frontiers in immunology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Judith SecklehnerCancer Research UK Beatson Institute, Garscube Campus, Glasgow, UK.
Cristina Lo CelsoDepartment of Life Sciences, Imperial College London, Sir Alexander Fleming Building, South Kensington, London, UK.
Leo M CarlinCancer Research UK Beatson Institute, Garscube Campus, Glasgow, UK.

Funding

Biotechnology and Biological Sciences Research Council BB/L023776/1Biotechnology and Biological Sciences Research Council P48528Cancer Research UK 11831Cancer Research UK 23983Cancer Research UK A23983Medical Research Council MR/M01245X/1Wellcome TrustWellcome Trust P49828
6 · The paper itself

Abstract

In this review, we discuss intravital microscopy of immune cells, starting from its historic origins to current applications in diverse organs. It is clear from a quantitative review of the literature that intravital microscopy is a key tool in both historic and contemporary immunological research, providing unique advances in our understanding of immune responses. We have chosen to focus this review on how intravital microscopy methodologies are used to image specific organs or systems and we present recent descriptions of fundamental immunological processes that could not have been achieved by other methods. The following target organs/systems are discussed in more detail: cremaster muscle, skin (ear and dorsal skin fold chamber), lymph node, liver, lung, mesenteric vessels, carotid artery, bone marrow, brain, spleen, foetus and lastly vessels of the knee joint.

Indexed as

Histological TechniquesImmunologic TechniquesAnimalsHumansIntravital Microscopy

Identifiers

PMID28366932
PMCPMC6095455

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.