Evidence map›Paper›PMID 28366830›Full record

ArticleJournal of molecular biology2017

Studying the Lysine Acetylation of Malate Dehydrogenase.

Sumana Venkat, Caroline Gregory, Jourdan Sturges, Qinglei Gan, Chenguang Fan

Open access · greenAbstract read
In one paragraph

Article in Journal of molecular biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 75 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Bacterial protein acetylation: mechanisms, functions, and methods for study.Frontiers in cellular and infection microbiology · 2024
    Review
  9. Article
  10. Characterizing lysine acetylation of glucokinase.Protein science : a publication of the Protein Society · 2024
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Antifungal Mechanism of Metabolites from Newly IsolatedJournal of fungi (Basel, Switzerland) · 2022
    Article
  17. Review
  18. Article
  19. Lysine acetylation ofFrontiers in bioengineering and biotechnology · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Sumana VenkatDepartment of Chemistry and Biochemistry, University of Arkansas, Fayetteville, AR 72701, USA; Cell and Molecular Biology Program, University of Arkansas, Fayetteville, AR 72701, USA.
Caroline GregoryDepartment of Biological Sciences, University of Arkansas, Fayetteville, AR 72701, USA.
Jourdan SturgesDepartment of Biological Sciences, University of Arkansas, Fayetteville, AR 72701, USA.
Qinglei GanDepartment of Chemistry and Biochemistry, University of Arkansas, Fayetteville, AR 72701, USA.
Chenguang FanDepartment of Chemistry and Biochemistry, University of Arkansas, Fayetteville, AR 72701, USA; Cell and Molecular Biology Program, University of Arkansas, Fayetteville, AR 72701, USA. Electronic address: cf021@uark.edu.
University of Arkansas at Fayetteville · US

Funding

Expanding the genetic code in SalmonellaR21AI119813 · NIAID · YALE UNIVERSITY · PI FAN, CHENGUANG · 2015 to 2016
$424k
NIAID NIH HHS R21 AI119813
6 · The paper itself

Abstract

Protein acetylation plays important roles in many biological processes. Malate dehydrogenase (MDH), a key enzyme in the tricarboxylic acid cycle, has been identified to be acetylated in bacteria by proteomic studies, but no further characterization has been reported. One challenge for studying protein acetylation is to get purely acetylated proteins at specific positions. Here, we applied the genetic code expansion strategy to site-specifically incorporate N

Indexed as

Protein Processing, Post-TranslationalAcetylationAcetyl Coenzyme AAcetyltransferasesCulture MediaEscherichia coliEscherichia coli ProteinsLysineMalate DehydrogenaseOrganophosphatesSirtuinsacetyl-CoA synthetase acetylase, E coliAcetyl Coenzyme Aacetyl phosphateAcetyltransferasescobB protein, E ColiCulture MediaEscherichia coli ProteinsLysineMalate DehydrogenaseOrganophosphatesSirtuinsacetyltransferasedeacetylasegenetic code expansionpost-translational modificationprotein acetylation

Identifiers

PMID28366830
PMCPMC5479488
OpenAlexW2597448223

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.