Evidence map›Paper›PMID 28366795›Full record

ArticleThe Journal of allergy and clinical immunology2018

β

Maya R Karta, Peter S Rosenthal, Andrew Beppu, Christine Y Vuong, Marina Miller, Sudipta Das, Richard C Kurten, Taylor A Doherty, David H Broide

Abstract read
In one paragraph

Article in The Journal of allergy and clinical immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 68 citations in OpenAlex.

  1. Article
  2. ILC2s and their immune checkpoints in the antitumor response.Journal for immunotherapy of cancer · 2026
    Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Innate Lymphoid Cells.Advances in experimental medicine and biology · 2025
    Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Innate lymphoid cells and cancer.Nature immunology · 2022
    Review
  17. Article
  18. Crosstalk between ILC2s and Th2 CD4Journal of immunology research · 2022
    Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Maya R KartaDepartment of Medicine, University of California San Diego, La Jolla, Calif.
Peter S RosenthalDepartment of Medicine, University of California San Diego, La Jolla, Calif.
Andrew BeppuDepartment of Medicine, University of California San Diego, La Jolla, Calif.
Christine Y VuongDepartment of Medicine, University of California San Diego, La Jolla, Calif.
Marina MillerDepartment of Medicine, University of California San Diego, La Jolla, Calif.
Sudipta DasDepartment of Medicine, University of California San Diego, La Jolla, Calif.
Richard C KurtenDepartment of Physiology and Biophysics, University of Arkansas for Medical Sciences and Arkansas Children's Hospital Research Institute, Little Rock, Ark.
Taylor A DohertyDepartment of Medicine, University of California San Diego, La Jolla, Calif.
David H BroideDepartment of Medicine, University of California San Diego, La Jolla, Calif. Electronic address: dbroide@ucsd.edu.
University of California San Diego · USArkansas Children's Hospital · US

Funding

TRM and airway inflammation and remodelingU19AI070535 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BROIDE, DAVID H · 2006 to 2025
$34.2M
TRAINING IN MOLECULAR &CELL BIOLOGY OF ALLERGYT32AI007469 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BROIDE, DAVID H · 1994 to 2024
$6.9M
Chromosome 17q, allergic inflammation, and remodelingR01AI107779 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BROIDE, DAVID H · 2013 to 2024
$4.7M
Eosinophil trafficking and chronic tissue damage induced by allergic inflammationR37AI038425 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BROIDE, DAVID H · 2007 to 2016
$3.7M
GSDMB and mucosal allergic responseR01AI124236 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BROIDE, DAVID H · 2017 to 2020
$2.4M
RBM3 regulation of type 2 innate lymphoid cells in allergic inflammationR01AI114585 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DOHERTY, TAYLOR A · 2015 to 2019
$2.3M
Eosinophil TraffickingR01AI038425 · NIAID · UNIVERSITY OF CALIFORNIA SAN DIEGO · PI BROIDE, DAVID H · 1996 to 2005
$1.8M
Siglec-F and Resolution of Allergic InflammationR01AI072115 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BROIDE, DAVID H · 2008 to 2012
$1.7M
NIAID NIH HHS R01 AI038425NIAID NIH HHS R01 AI072115NIAID NIH HHS R01 AI107779NIAID NIH HHS R01 AI114585NIAID NIH HHS R01 AI124236NIAID NIH HHS R37 AI038425NIAID NIH HHS T32 AI007469NIAID NIH HHS U19 AI070535
6 · The paper itself

Abstract

backgroundGroup 2 innate lymphoid cells (ILC2s) expand in the lungs of mice during type 2 inflammation induced by the fungal allergen Alternaria alternata. The increase in ILC2 numbers in the lung has been largely attributed to local proliferation and whether ILC2s migrate from the circulation to the lung after Alternaria exposure is unknown.

objectiveWe examined whether human (lung, lymph node, and blood) and mouse lung ILC2s express β

methodsHuman and mouse ILC2s were assessed for surface expression of β

resultsBoth human and mouse lung ILC2s express high levels of β

conclusionILC2 numbers increase in the mouse lung not only through local proliferation but also through trafficking from the circulation into the lung using β

Indexed as

Immunity, InnateAlternariaAnimalsApoptosisBiomarkersBone MarrowCD18 AntigensCytokinesFlow CytometryGene ExpressionHumansIntegrin beta1Intercellular Adhesion Molecule-1L-SelectinLungLymphocyte CountBiomarkersCD18 AntigensCytokinesIntegrin beta1Intercellular Adhesion Molecule-1L-SelectinadhesionAlternaria alternataGroup 2 innate lymphoid cellintegrin

Identifiers

PMID28366795
PMCPMC5623168
OpenAlexW2602458551

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.