Evidence map›Paper›PMID 28366532›Full record

ReviewCurrent opinion in neurobiology2017

The Drosophila circuitry of sleep-wake regulation.

Gregory Artiushin, Amita Sehgal

Abstract readReview
In one paragraph

Review in Current opinion in neurobiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed.

  1. Invertebrate brains as diversified models for understanding sleep mechanisms and function.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2026
    Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. On analogies in vertebrate and insect visual systems.Nature reviews. Neuroscience · 2025
    Review
  7. Article
  8. Article
  9. Activity Monitoring for Analysis of Sleep inCold Spring Harbor protocols · 2024
    Article
  10. Article
  11. Article
  12. iScience · 2024
    Article
  13. Article
  14. Article
  15. Article
  16. Low-nutrient diet inOpen biology · 2023
    Article
  17. Widespread post-transcriptional regulation of co-transmission.bioRxiv : the preprint server for biology · 2023
    Article
  18. Subtype-Specific Roles of Ellipsoid Body Ring Neurons in Sleep Regulation inThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  19. Article
  20. Article

8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Gregory ArtiushinHoward Hughes Medical Institute, Chronobiology Program, University of Pennsylvania, Philadelphia, PA 19104, USA.
Amita SehgalHoward Hughes Medical Institute, Chronobiology Program, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: amita@mail.med.upenn.edu.

Funding

Training in Sleep & Sleep DisordersT32HL007953 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI David Menassah Raizen, AMY M SAWYER · 2000 to 2026
$10.6M
Howard Hughes Medical InstituteNHLBI NIH HHS T32 HL007953
6 · The paper itself

Abstract

Sleep is a deeply conserved, yet fundamentally mysterious behavioral state. Knowledge of the circuitry of sleep-wake regulation is an essential step in understanding the physiology of the sleeping brain. Recent efforts in Drosophila have revealed new populations which impact sleep, as well as provided unprecedented mechanistic and electrophysiological detail of established sleep-regulating neurons. Multiple, distributed centers of sleep-wake circuitry exist in the fly, including the mushroom bodies, central complex and the circadian clock cells. Intriguingly, certain populations have been implicated in specific roles in homeostatic rebound sleep, occurring after sleep loss. In short, our knowledge of fly sleep circuitry advances towards a greater view of brain-wide connectivity and integration of the signals and correlates of the state of sleep.

Indexed as

AnimalsBrainCircadian RhythmDrosophilaMushroom BodiesSleepWakefulness

Identifiers

PMID28366532
PMCPMC10826075

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.