ReviewFertility and sterility2017
Adverse effects of female obesity and interaction with race on reproductive potential.
Review in Fertility and sterility, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04113070 (The Effect of Childhood Overweight and Obesity and Genetic Factors on Puberty Development), which is not on this map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of Childhood Overweight and Obesity and Genetic Factors on Puberty Development: a Prospective Cohort Study
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 69 citations in OpenAlex.
- Comparison of exenatide alone or combined with metformin versus metformin in the treatment of polycystic ovaries: a systematic review and meta-analysis.BMC endocrine disorders · 2023Pooled it
- Metabolic syndrome in obesity: treatment success and adverse pregnancy outcomes with ovulation induction in polycystic ovary syndrome.American journal of obstetrics and gynecology · 2021Trial
- Adiposity is associated with anovulation independent of serum free testosterone: A prospective cohort study.Paediatric and perinatal epidemiology · 2021Trial
- Modeling Diagnosis and Clinical Outcomes in Infertility Couples Considering Multiple Factors: A Retrospective Study.International journal of fertility & sterility · 2026Article
- Characterization of infertile couples and outcomes of their first in vitro fertilization cycle at public fertility centers in Northern and Central Portugal: a five-year cohort study.JBRA assisted reproduction · 2025Observational
- Obesity Epidemic and Its Impact on Female Fertility: Current Understanding and Future Directions.Cureus · 2025Review
- Impact of race and ethnicity on in vitro fertilization outcomes in infertile women with polycystic ovary syndrome in the United States.F&S reports · 2025Article
- Therapeutic effects and potential mechanisms of caffeine on obese polycystic ovary syndrome: bioinformatic analysis and experimental validation.Scientific reports · 2025Article
- Are there associations between clinical and embryological factors with pregnancy loss following transfer of a single euploid embryo?Reproduction & fertility · 2024Article
- Effect of Paternal Body Mass Index onThe world journal of men's health · 2024Article
- Metabolic Syndrome and Assisted Reproductive Techniques.Journal of family & reproductive health · 2023Article
- The influence of male and female overweight/obesity on IVF outcomes: a cohort study based on registration in Western China.Reproductive health · 2023Article
- Editorial: Advances and perspectives in neuroplacentology.Frontiers in endocrinology · 2023Article
- Racial differences in the associations between adiposity, placental growth hormone and inflammatory cytokines in pregnant women.Frontiers in endocrinology · 2023Article
- Reprotoxic Impact of Environment, Diet, and Behavior.International journal of environmental research and public health · 2022Review
- Overweight and obesity significantly reduce pregnancy, implantation, and live birth rates in women undergoing In Vitro Fertilization procedures.JBRA assisted reproduction · 2021Article
- Adverse effects of pre-pregnancy maternal underweight on pregnancy and perinatal outcomes in a freeze-all policy.BMC pregnancy and childbirth · 2021Article
- Does body mass index impact assisted reproductive technology treatment outcomes in gestational carriers.Reproductive biology and endocrinology : RB&E · 2020Article
- The association between preconception body mass index and subfertility among Hispanic and non-Hispanic women: A cross-sectional study from Utah's Pregnancy Risk Assessment Monitoring System survey (2012-2015).The Utah women's health review · 2020Article
- Effect of body mass index on pregnancy outcomes in a freeze-all policy: an analysis of 22,043 first autologous frozen-thawed embryo transfer cycles in China.BMC medicine · 2019 · on this mapArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Across the reproductive spectrum, obesity is associated with greater risks for adverse health outcomes, including higher rates of infertility, subfertility, early pregnancy loss, fetal deaths and stillbirths, congenital anomalies, and pregnancy complications. The excess reproductive morbidity associated with obesity may increase with longer duration, making the current trends among children and young adults particularly critical in terms of their future reproductive potential. Obese women have a lower chance of pregnancy following in vitro fertilization (IVF), require higher dosages of gonadotropins, and have reduced rates of implantation, clinical intrauterine gestation, and live birth rates and increased rates of pregnancy loss, as well as greater risks for prematurity and preeclampsia even when stratified by plurality. Racial and ethnic differences by overweight and obesity in IVF outcomes have been reported. Compared with normal-weight women, failure to achieve a clinical intrauterine gestation is significantly more likely among obese women overall, normal-weight and obese Asian women, normal-weight Hispanic women, and overweight and obese Black women. Among women who do conceive, compared with normal-weight women, failure to achieve a live birth is significantly more likely among overweight and obese women overall, and among overweight and obese Asian women, overweight and obese Hispanic women, and normal-weight and obese Black women. Although weight loss should theoretically be the first line of therapy for obese women, other lifestyle factors, such as regular physical exercise, elimination of tobacco use and alcohol consumption, and stress management, may be of more immediate benefit in achieving conception.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.