Evidence map›Paper›PMID 28366041›Full record

ArticleJournal of immunotoxicology2017

A single dose of trichloroethylene given during development does not substantially alter markers of neuroinflammation in brains of adult mice.

Jacqueline R Meadows, Chevonne Parker, Kathleen M Gilbert, Sarah J Blossom, Jamie C DeWitt

Open access · goldAbstract read
In one paragraph

Article in Journal of immunotoxicology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jacqueline R Meadowsa Department of Pharmacology and Toxicology , Brody School of Medicine, East Carolina University Greenville , NC , USA.
Chevonne Parkera Department of Pharmacology and Toxicology , Brody School of Medicine, East Carolina University Greenville , NC , USA.
Kathleen M Gilbertb Department of Microbiology and Immunology , UAMS College of Medicine, Arkansas Children's Research Institute , Little Rock , AR , USA.
Sarah J Blossomc Department of Pediatrics , UAMS College of Medicine, Arkansas Children's Research Institute , Little Rock , AR , USA.
Jamie C DeWitta Department of Pharmacology and Toxicology , Brody School of Medicine, East Carolina University Greenville , NC , USA.
East Carolina University · USArkansas Children's Hospital · US

Funding

Developmental programming of TCE induced autoimmune diseaseR01ES021484 · NIEHS · ARKANSAS CHILDREN'S HOSPITAL RES INST · PI BLOSSOM, SARAH J, GILBERT, KATHLEEN M · 2013 to 2016
$1.4M
CD4+ T cell-mediated neurotoxicity with continuous trichloroethylene exposureK02ES024387 · NIEHS · ARKANSAS CHILDREN'S HOSPITAL RES INST · PI BLOSSOM, SARAH J · 2014 to 2018
$674k
NIEHS NIH HHS K02 ES024387NIEHS NIH HHS R01 ES021484
6 · The paper itself

Abstract

Trichloroethylene (TCE) is a widespread environmental contaminant associated with developmental immunotoxicity and neurotoxicity. Previous studies have shown that MRL

Indexed as

AnimalsBiomarkersBrainCD4-Positive T-LymphocytesCells, CulturedEnvironmental PollutionFemaleFetal DevelopmentInflammation MediatorsInterleukin-10Interleukin-6MiceMice, Inbred MRL lprNeurogenic InflammationOxidative StressPregnancyBiomarkersInflammation MediatorsInterleukin-10Interleukin-6Trichloroethylenebraindevelopmentalearly-lifemicroglianeuroinflammationTrichloroethylene

Identifiers

PMID28366041
PMCPMC5540234
OpenAlexW2605332805

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.