ArticleEuropean journal of nuclear medicine and molecular imaging2017
Single-scan rest/stress imaging: validation in a porcine model with
Article in European journal of nuclear medicine and molecular imaging, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Added value of myocardial blood flow usingJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Trial
- Technical evaluation of immediate back-to-back rest-stress positron emission tomography scanning withJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2025Article
- Comparative evaluation of a novel [European journal of nuclear medicine and molecular imaging · 2025Article
- Preclinical Validation of a Single-Scan Rest/Stress Imaging Technique forCirculation. Cardiovascular imaging · 2020Article
- Moving into the next era of PET myocardial perfusion imaging: introduction of novelThe international journal of cardiovascular imaging · 2019Review
- Quantification of PET Myocardial Blood Flow.Current cardiology reports · 2019Review
- Joint reconstruction of rest/stress myocardial perfusion SPECT.Physics in medicine and biology · 2018Article
- Searching for novel PET radiotracers: imaging cardiac perfusion, metabolism and inflammation.American journal of nuclear medicine and molecular imaging · 2018Review
- Rapid computation of single PET scan rest-stress myocardial blood flow parametric images by table look up.Medical physics · 2017Article
- Direct parametric reconstruction in dynamic PET myocardial perfusion imaging: in vivo studies.Physics in medicine and biology · 2017Article
- Impact of motion and partial volume effects correction on PET myocardial perfusion imaging using simultaneous PET-MR.Physics in medicine and biology · 2017Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose
methodsSingle-scan rest-stress measurements were made using
resultsThe first 12-14 minutes of rest-stress PET data were fitted in detail by the MGH2 model, yielding MBF measurement with a mean precision of 0.035 ml/min/cc. Mean myocardial blood flow across pigs was 0.61 ± 0.11 mL/min/cc at rest and 1.06 ± 0.19 mL/min/cc at stress in healthy pigs and 0.36 ± 0.20 mL/min/cc at rest and 0.62 ± 0.24 mL/min/cc at stress in the ischemic area. Good agreement was obtained with microsphere flow measurement (slope = 1.061 ± 0.017, intercept = 0.051 ± 0.017, mean difference 0.096 ± 0.18 ml/min/cc).
conclusionAccurate rest and stress blood flow estimation can be obtained in less than 15 min of PET acquisition. The method is practical and easy to implement suggesting the possibility of clinical translation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.