Evidence map›Paper›PMID 28365457›Full record

ArticleAntiviral research2017

The history of rabies in the Western Hemisphere.

Andres Velasco-Villa, Matthew R Mauldin, Mang Shi, Luis E Escobar, Nadia F Gallardo-Romero, Inger Damon, Victoria A Olson, Daniel G Streicker, Ginny Emerson

Open access · hybridAbstract readHistorical Article
In one paragraph

Article in Antiviral research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed
7.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 154 citations in OpenAlex.

  1. Review
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  6. First isolation of rabies virus from a Eurasian badger (Frontiers in veterinary science · 2025
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  11. Review
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  19. On skunk rabies and its prevention in North America.Equine veterinary education · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Andres Velasco-VillaDivision of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, 1600 Clifton Rd, NE, Atlanta, 30329, GA, USA. Electronic address: DLY3@CDC.GOV.
Matthew R MauldinDivision of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, 1600 Clifton Rd, NE, Atlanta, 30329, GA, USA; Oak Ridge Institute for Science and Education (ORISE), CDC Fellowship Program, Oak Ridge, TN, USA.
Mang ShiCharles Perkins Centre, School of Life and Environmental Sciences and Sydney Medical School, The University of Sydney, Sydney, NSW, 2006, Australia.
Luis E EscobarDepartment of Fisheries, Wildlife and Conservation Biology, University of Minnesota, Saint Paul, 55108, MN, USA.
Nadia F Gallardo-RomeroDivision of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, 1600 Clifton Rd, NE, Atlanta, 30329, GA, USA.
Inger DamonDivision of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, 1600 Clifton Rd, NE, Atlanta, 30329, GA, USA.
Victoria A OlsonDivision of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, 1600 Clifton Rd, NE, Atlanta, 30329, GA, USA.
Daniel G StreickerInstitute of Biodiversity, Animal Health and Comparative Medicine, University of Glasgow, Graham Kerr Building, Glasgow, G12 8QQ, Scotland, UK; MRC-University of Glasgow Centre for Virus Research, Sir Henry Wellcome Building, Glasgow, G61 1QH, Scotland, UK.
Ginny EmersonDivision of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, 1600 Clifton Rd, NE, Atlanta, 30329, GA, USA.
Centers for Disease Control and Prevention · USMRC University of Glasgow Centre for Virus Research · GBOak Ridge Associated Universities · USThe University of Sydney · AUUniversity of Minnesota · US

Funding

Intramural CDC HHS CC999999Medical Research Council MC_UU_12014/8
6 · The paper itself

Abstract

Before the introduction of control programs in the 20th century, rabies in domestic dogs occurred throughout the Western Hemisphere. However, historical records and phylogenetic analysis of multiple virus isolates indicate that, before the arrival of the first European colonizers, rabies virus was likely present only in bats and skunks. Canine rabies was either rare or absent among domestic dogs of Native Americans, and first arrived when many new dog breeds were imported during the period of European colonization. The introduction of the cosmopolitan dog rabies lyssavirus variant and the marked expansion of the dog population provided ideal conditions for the flourishing of enzootic canine rabies. The shift of dog-maintained viruses into gray foxes, coyotes, skunks and other wild mesocarnivores throughout the Americas and to mongooses in the Caribbean has augmented the risk of human rabies exposures and has complicated control efforts. At the same time, the continued presence of bat rabies poses novel challenges in the absolute elimination of canine and human rabies. This article compiles existing historical and phylogenetic evidence of the origins and subsequent dynamics of rabies in the Western Hemisphere, from the era preceding the arrival of the first European colonizers through the present day. A companion article reviews the current status of canine rabies control throughout the Western Hemisphere and steps that will be required to achieve and maintain its complete elimination (Velasco-Villa et al., 2017).

Indexed as

AnimalsAnimals, WildCattleCenters for Disease Control and Prevention, U.S.ChiropteraDog DiseasesDogsEuropeFoxesHistory, 19th CenturyHistory, 20th CenturyHumansLyssavirusPhylogenyPopulation SurveillancePublic Health

Identifiers

PMID28365457
PMCPMC5620125
OpenAlexW2602140745

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.