Evidence map›Paper›PMID 28365422›Full record

ArticleJournal of molecular and cellular cardiology2017

Mechanisms of the cyclic nucleotide cross-talk signaling network in cardiac L-type calcium channel regulation.

Claire Y Zhao, Joseph L Greenstein, Raimond L Winslow

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of molecular and cellular cardiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Claire Y ZhaoDepartment of Biomedical Engineering and the Institute for Computational Medicine, The Johns Hopkins University School of Medicine and Whiting School of Engineering, 3400 N Charles Street, Baltimore, MD, 21218, USA. Electronic address: czhao10@jhu.edu.
Joseph L GreensteinDepartment of Biomedical Engineering and the Institute for Computational Medicine, The Johns Hopkins University School of Medicine and Whiting School of Engineering, 3400 N Charles Street, Baltimore, MD, 21218, USA. Electronic address: jgreenst@jhu.edu.
Raimond L WinslowDepartment of Biomedical Engineering and the Institute for Computational Medicine, The Johns Hopkins University School of Medicine and Whiting School of Engineering, 3400 N Charles Street, Baltimore, MD, 21218, USA. Electronic address: rwinslow@jhu.edu.
Johns Hopkins Medicine · USJohns Hopkins University · US

Funding

Calcium Entrained ArrhythmiasR01HL105239 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI JAFRI, MOHSIN SALEET, LEDERER, WILLIAM JONATHAN · 2011 to 2015
$4.9M
NHLBI NIH HHS R01 HL105239
6 · The paper itself

Abstract

Regulation of L-type Calcium (Ca

Indexed as

Action PotentialsCalcium Channels, L-TypeComputer SimulationCyclic AMP-Dependent Protein KinasesCyclic GMPCyclic GMP-Dependent Protein KinasesCyclic Nucleotide-Gated Cation ChannelsCyclic Nucleotide Phosphodiesterases, Type 4Heart RateHumansMyocardial ContractionMyocytes, CardiacNitric OxideNucleotidesPhosphorylationReceptors, Adrenergic, betaCalcium Channels, L-TypeCyclic AMP-Dependent Protein KinasesCyclic GMPCyclic GMP-Dependent Protein KinasesCyclic Nucleotide-Gated Cation ChannelsCyclic Nucleotide Phosphodiesterases, Type 4Nitric OxideNucleotidesReceptors, Adrenergic, betaCardiac myocytesComputational modelCyclic nucleotidesL-type calcium channelPhosphodiesterasesSignaling network

Identifiers

PMID28365422
PMCPMC5508987
OpenAlexW2603798109

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.