ArticleSurgical endoscopy2017
Increased identification of parathyroid glands using near infrared light during thyroid and parathyroid surgery.
Article in Surgical endoscopy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 51 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Precise Recognition With Enhanced Vision of Endocrine Neck Targets
Usefulness of ICG Angiography-Guided Thyroidectomy for Preserving Parathyroid Function. GuiArte Multicentric Randomized Study.
Who cites it
51 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Fluorescent Imaging in Thyroid Surgery to Preserve Parathyroid Function: A Systematic Review and Meta-Analysis.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2026Pooled it
- Near-infrared autofluorescence-based parathyroid glands identification in the thyroidectomy or parathyroidectomy: a systematic review and meta-analysis.Langenbeck's archives of surgery · 2022Pooled it
- The Ability of Near-Infrared Autofluorescence to Protect Parathyroid Gland Function During Thyroid Surgery: A Meta-Analysis.Frontiers in endocrinology · 2021Pooled it
- Effect of near infrared autofluorescence guided total thyroidectomy on postoperative hypoparathyroidism: a randomized clinical trial.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023Trial
- Near-infrared autofluorescence of the parathyroid glands during thyroidectomy for the prevention of hypoparathyroidism: a prospective randomized clinical trial.Langenbeck's archives of surgery · 2022Trial
- Evaluation of Autofluorescence in Identifying Parathyroid Glands by Measuring Parathyroid Hormone in Fine-Needle Biopsy Washings.Frontiers in endocrinology · 2021Trial
- Illuminating the future: assessing probe-based near-infrared autofluorescence for parathyroid detection in endocrine surgery.Gland surgery · 2026Article
- Identification of Parathyroid Glands Through Near-Infrared Autofluorescence During Thyroid Surgery: Retrospective Analysis of the Impact on Post-Operative Hypocalcemia Rate Reduction and Potential Improvement of Healthcare Expenditure.Medicina (Kaunas, Lithuania) · 2025Article
- The research progress of label-free optical imaging technology in intraoperative real-time navigation of parathyroid glands.Lasers in medical science · 2025Review
- Thyroid surgery under nerve auto-fluorescence & artificial intelligence tissue identification software guidance.Langenbeck's archives of surgery · 2025Review
- Exploring near-infrared autofluorescence properties in parathyroid tissue: an analysis of fresh and paraffin-embedded thyroidectomy specimens.Journal of biomedical optics · 2025Article
- Autofluorescence-Guided Total Thyroidectomy in Low-Volume, Nonparathyroid Institutions.JAMA network open · 2024Article
- Improvement in Central Neck Dissection Quality in Thyroid Cancer by Use of Tissue Autofluorescence.Cancers · 2024Article
- Article
- Methods for the identification and preservation of parathyroid glands in thyroid surgery: a narrative review.Gland surgery · 2023Review
- Recent Advances in the Surgical Management of Thyroid Cancer.Current oncology (Toronto, Ont.) · 2023Review
- The Utility of Near-Infrared Autofluorescence for Parathyroid Gland Identification During Thyroid Surgery: A Single-Center Experience.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2023Article
- The magic mirror: a novel intraoperative monitoring method for parathyroid glands.Frontiers in endocrinology · 2023Review
- Central node dissection in papillary thyroid carcinoma in the era of near-infrared fluorescence.Frontiers in endocrinology · 2023Review
- Near-infrared fluorescent imaging for parathyroid identification and/or preservation in surgery for primary hyperparathyroidism.Frontiers in endocrinology · 2023Observational
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundParathyroid gland (PG) identification during thyroid and parathyroid surgery is challenging. Accidental parathyroidectomy increases the rate of postoperative hypocalcaemia. Recently, autofluorescence with near infrared light (NIRL) has been described for PG visualization. The aim of this study is to analyze the increased rate of visualization of PGs with the use of NIRL compared to white light (WL). MATERIALS AND
methodsAll patients undergoing thyroid and parathyroid surgery were included in this study. PGs were identified with both NIRL and WL by experienced head and neck surgeons. The number of PGs identified with NIRL and WL were compared. The identification of PGs was correlated to age, sex, and histopathological diagnosis.
resultsSeventy-four patients were included in the study. The mean age was 48.4 (SD ±13.5) years old. Mean PG fluorescence intensity (47.60) was significantly higher compared to the thyroid gland (22.32) and background (9.27) (p < 0.0001). The mean number of PGs identified with NIRL and WL were 3.7 and 2.5 PG, respectively (p < 0.001). The difference in the number of PGs identified with NIRL and WL and fluorescence intensity was not related to age, sex, or histopathological diagnosis, with the exception of the diagnosis of thyroiditis, in which there was a significant increase in the number of PGs visualized with NIRL (p = 0.026).
conclusionThe use of NIRL for PG visualization significantly increased the number of PGs identified during thyroid and parathyroid surgery, and the differences in fluorescent intensity among PGs, thyroid glands, and background were not affected by age, sex, and histopathological diagnosis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.