Evidence map›Paper›PMID 28364043›Full record

ArticleThe Journal of biological chemistry2017

Unraveling the structural basis for the unusually rich association of human leukocyte antigen DQ2.5 with class-II-associated invariant chain peptides.

Thanh-Binh Nguyen, Priya Jayaraman, Elin Bergseng, M S Madhusudhan, Chu-Young Kim, Ludvig M Sollid

Abstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Article
  3. Structural insights into human MHC-II association with invariant chain.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  4. A general platform for targeting MHC-II antigens via a single loop.bioRxiv : the preprint server for biology · 2024
    Article
  5. Analysis of CD74 Occurrence in Oncogenic Fusion Proteins.International journal of molecular sciences · 2023
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Multiple autoimmunity and epitope spreading in monozygotic twins.Journal of translational autoimmunity · 2021
    Article
  11. Article
  12. Review
  13. HLA-DO Modulates the Diversity of the MHC-II Self-peptidome.Molecular & cellular proteomics : MCP · 2019
    Article
  14. Review
  15. Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Thanh-Binh Nguyenthe Bioinformatics Institute, Singapore 138671, Singapore.
Priya Jayaramanthe Department of Biological Sciences, National University of Singapore, Singapore 117543, Singapore.
Elin Bergsengthe Centre for Immune Regulation and Department of Immunology, University of Oslo and Oslo University Hospital, N-0372 Oslo, Norway.
M S Madhusudhanthe Bioinformatics Institute, Singapore 138671, Singapore.
Chu-Young KimFrom the Department of Chemistry and ckim7@utep.edu.
Ludvig M Sollidthe Centre for Immune Regulation and Department of Immunology, University of Oslo and Oslo University Hospital, N-0372 Oslo, Norway l.m.sollid@medisin.uio.no.

Funding

X-ray Absorption Spectroscopy (XAS) pp.711-759P41GM103393 · NIGMS · STANFORD UNIVERSITY · PI HODGSON, KEITH O · 2012 to 2019
$30.6M
NIGMS NIH HHS P41 GM103393
6 · The paper itself

Abstract

Human leukocyte antigen (HLA)-DQ2.5 (

Indexed as

Molecular Dynamics SimulationBinding SitesHLA-DQ alpha-ChainsHLA-DQ AntigensHLA-DQ beta-ChainsHumansPeptidesHLA-DQ2 antigenHLA-DQA1 antigenHLA-DQ alpha-ChainsHLA-DQ AntigensHLA-DQB1 antigenHLA-DQ beta-ChainsPeptidesautoimmune diseaseceliac diseaseHLA-DMHLA-DQmajor histocompatibility complex (MHC)molecular dynamicstype 1 diabetesX-ray crystallography

Identifiers

PMID28364043
PMCPMC5454103

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.