Evidence map›Paper›PMID 28364022›Full record

ArticleEMBO reports2017

The phosphorylation status of T522 modulates tissue-specific functions of SIRT1 in energy metabolism in mice.

Jing Lu, Qing Xu, Ming Ji, Xiumei Guo, Xiaojiang Xu, David C Fargo, Xiaoling Li

Open access · hybridAbstract read
In one paragraph

Article in EMBO reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jing LuSignal Transduction Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA.
Qing XuSignal Transduction Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA.
Ming JiSignal Transduction Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA.
Xiumei GuoSignal Transduction Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA.
Xiaojiang XuIntegrative Bioinformatics, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA.
David C FargoIntegrative Bioinformatics, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA.
Xiaoling LiSignal Transduction Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA lix3@niehs.nih.gov.ORCID 0000-0001-5920-7784
National Institute of Environmental Health Sciences · US

Funding

Sirtuins and nuclear receptors in aging and age-associated diseasesZIAES102205 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI LI, XIAOLING · 2009 to 2025
$42.4M
Gene Expression and MicroarraysZICES102445 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI GERRISH, KEVIN · 2009 to 2025
$31.6M
6 · The paper itself

Abstract

SIRT1, the most conserved mammalian NAD

Indexed as

AdipogenesisEnergy MetabolismAdipocytesAnimalsCell DifferentiationDiet, High-FatDyslipidemiasFatty LiverFemaleGATA3 Transcription FactorGene Expression RegulationMaleMicePhosphorylationSirtuin 1ThreonineGata3 protein, mouseGATA3 Transcription FactorSirt1 protein, mouseSirtuin 1Threonineadipogenesishepatic steatosisliver damagephosphorylationSIRT1

Identifiers

PMID28364022
PMCPMC5412809
OpenAlexW2598459868

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.