Evidence map›Paper›PMID 28364014›Full record

ArticleClinical cancer research : an official journal of the American Association for Cancer Research2017

Radium-223 Inhibits Osseous Prostate Cancer Growth by Dual Targeting of Cancer Cells and Bone Microenvironment in Mouse Models.

Mari I Suominen, Katja M Fagerlund, Jukka P Rissanen, Yvonne M Konkol, Jukka P Morko, ZhiQi Peng, Esa J Alhoniemi, Salla K Laine, Eva Corey, Dominik Mumberg and 5 more

Open access · greenAbstract read
In one paragraph

Article in Clinical cancer research : an official journal of the American Association for Cancer Research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 91 papers.

0numbers the graph read from it
0cells of the map it votes in
91citing papers in PubMed
16.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

91 citing papers in PubMed, 174 citations in OpenAlex.

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  7. Biokinetic modelling of the exhalation ofRadiation and environmental biophysics · 2026
    Article
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  11. Dissecting the effects ofActa pharmaceutica Sinica. B · 2025
    Article
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  14. EJNMMI radiopharmacy and chemistry · 2025
    Review
  15. Exploring the Therapeutic Potential ofInternational journal of molecular sciences · 2025
    Article
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  20. Biomarkers of bone metabolism in [EJNMMI research · 2024
    Article

31 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 2 countries.

Mari I SuominenPharmatest Services Ltd., Turku, Finland.
Katja M FagerlundPharmatest Services Ltd., Turku, Finland.
Jukka P RissanenPharmatest Services Ltd., Turku, Finland.
Yvonne M KonkolPharmatest Services Ltd., Turku, Finland.
Jukka P MorkoPharmatest Services Ltd., Turku, Finland.
ZhiQi PengPharmatest Services Ltd., Turku, Finland.
Esa J AlhoniemiAvoltus Oy, Turku, Finland.
Salla K LaineAurexel Life Sciences Ltd., Askainen, Finland.
Eva CoreyDepartment of Urology, University of Washington, Seattle, Washington.
Dominik MumbergBayer AG, Pharmaceuticals Division, Drug Discovery, Therapeutic Research Groups Oncology, Berlin, Germany.
Karl ZiegelbauerBayer AG, Pharmaceuticals Division, Drug Discovery, Therapeutic Research Groups Oncology, Berlin, Germany.
Sanna-Maria KäkönenAurexel Life Sciences Ltd., Askainen, Finland.
Jussi M HalleenPharmatest Services Ltd., Turku, Finland.
Robert L VessellaDepartment of Urology, University of Washington, Seattle, Washington.
Arne ScholzBayer AG, Pharmaceuticals Division, Drug Discovery, Therapeutic Research Groups Oncology, Berlin, Germany. arne.scholz@bayer.com.
Pharmatest (Finland) · FIUniversity of Washington · US

Funding

TRANSCRIPTOME AND PROTEOME STRATIFICATION OF PROSTATE ADENOCARCINOMA PHENOTYPESP50CA097186 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI PETER S NELSON · 2002 to 2026
$58.1M
Steroid Metabolism in Castration-Resistant Prostate CancerP01CA163227 · NCI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI PETER S NELSON · 2013 to 2026
$25.0M
Transmembrane Proteases and Prostate CarcinogenesisP01CA085859 · NCI · UNIVERSITY OF WASHINGTON · PI VESSELLA, ROBERT LOUIS · 2002 to 2013
$21.2M
NCI NIH HHS P01 CA085859NCI NIH HHS P01 CA163227NCI NIH HHS P50 CA097186
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAntineoplastic AgentsBone and BonesBone NeoplasmsCell Line, TumorCell ProliferationDisease Models, AnimalHumansMaleMiceOsteoclastsProstatic Neoplasms, Castration-ResistantRadioisotopesRadiumTumor MicroenvironmentAntineoplastic AgentsRadioisotopesRadiumRadium-223

Identifiers

PMID28364014
PMCPMC5540794
OpenAlexW2604062834

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.