Evidence map›Paper›PMID 28363984›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2017

Blood Pressure Regulation by the Rostral Ventrolateral Medulla in Conscious Rats: Effects of Hypoxia, Hypercapnia, Baroreceptor Denervation, and Anesthesia.

Ian C Wenker, Chikara Abe, Kenneth E Viar, Daniel S Stornetta, Ruth L Stornetta, Patrice G Guyenet

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 75 citations in OpenAlex.

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  13. Adrenergic C1 neurons enhance anxiety via projections to PAG.bioRxiv : the preprint server for biology · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ian C WenkerDepartment of Pharmacology, University of Virginia, Charlottesville, Virginia 22908.
Chikara AbeDepartment of Pharmacology, University of Virginia, Charlottesville, Virginia 22908.
Kenneth E ViarDepartment of Pharmacology, University of Virginia, Charlottesville, Virginia 22908.
Daniel S StornettaDepartment of Pharmacology, University of Virginia, Charlottesville, Virginia 22908.
Ruth L StornettaDepartment of Pharmacology, University of Virginia, Charlottesville, Virginia 22908.ORCID 0000-0001-7278-8923
Patrice G GuyenetDepartment of Pharmacology, University of Virginia, Charlottesville, Virginia 22908 pgg@virginia.edu.ORCID 0000-0003-1739-2306
University of Virginia · US

Funding

Retrotrapezoid nucleus and central chemoreceptionR01HL074011 · NHLBI · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI GUYENET, PATRICE G. · 2003 to 2018
$6.6M
NDEWS Diversity Supplement: Exploring the Viability of Different Social Media Platforms for Emerging Drug Term DiscoveryU01DA038360 · NIDA · UNIV OF MARYLAND, COLLEGE PARK · PI WISH, ERIC D · 2014 to 2019
$5.0M
Organization of Central Sympathic PathwaysR01HL028785 · NHLBI · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI STORNETTA, RUTH L · 1985 to 2020
$5.0M
Brainstem control of blood pressure in conscious rodentsF32HL127975 · NHLBI · UNIVERSITY OF VIRGINIA · PI WENKER, IAN CHRISTOPHER · 2015 to 2016
$109k
NHLBI NIH HHS F32 HL127975NHLBI NIH HHS R01 HL028785NHLBI NIH HHS R01 HL074011NIDA NIH HHS U01 DA038360
6 · The paper itself

Abstract

Current understanding of the contribution of C1 neurons to blood pressure (BP) regulation derives predominantly from experiments performed in anesthetized animals or reduced

Indexed as

AnesthesiaBlood PressurePressoreceptorsAnesthetics, InhalationAnimalsChemoreceptor CellsHypercapniaHypertensionHypoxiaIsofluraneMaleMedulla OblongataNeuronsOptogeneticsRatsRats, Sprague-DawleyAnesthetics, InhalationIsofluranebaroreceptorblood pressurechemoreflexoptogeneticsRVLMsympathetic

Identifiers

PMID28363984
PMCPMC5413188
OpenAlexW2600107558

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.