Evidence map›Paper›PMID 28363980›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2017

A Presynaptic Group III mGluR Recruits Gβγ/SNARE Interactions to Inhibit Synaptic Transmission by Cone Photoreceptors in the Vertebrate Retina.

Matthew J Van Hook, Norbert Babai, Zack Zurawski, Yun Young Yim, Heidi E Hamm, Wallace B Thoreson

Open access · greenAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.3field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Article
  3. Cellular Physiology and Pathophysiology of EAAT Anion Channels.Frontiers in cellular neuroscience · 2021
    Review
  4. Transducin Partners Outside the Phototransduction Pathway.Frontiers in cellular neuroscience · 2020
    Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Matthew J Van HookTruhlsen Eye Institute, Department of Ophthalmology and Visual Sciences, University of Nebraska Medical Center, Omaha, Nebraska 68198, matt.vanhook@unmc.edu.ORCID 0000-0003-1615-4314
Norbert BabaiDepartment of Biology, Animal Physiology, University of Erlangen-Nuremberg, 91058 Erlangen, Germany.ORCID 0000-0002-9348-0546
Zack ZurawskiDepartment of Pharmacology, Vanderbilt University Medical School, Nashville, Tennessee 37232, and.
Yun Young YimDepartment of Pharmacology, Vanderbilt University Medical School, Nashville, Tennessee 37232, and.ORCID 0000-0002-0061-6820
Heidi E HammDepartment of Pharmacology, Vanderbilt University Medical School, Nashville, Tennessee 37232, and.ORCID 0000-0001-5437-5287
Wallace B ThoresonTruhlsen Eye Institute, Department of Ophthalmology and Visual Sciences, University of Nebraska Medical Center, Omaha, Nebraska 68198.ORCID 0000-0001-7104-042X
Vanderbilt University · USUniversity of Nebraska Medical Center · USFriedrich-Alexander-Universität Erlangen-Nürnberg · DE

Funding

Regulation of Photoreceptor NeurotransmisssionR01EY010542 · NEI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI KARATEKIN, ERDEM, THORESON, WALLACE B · 2001 to 2023
$7.7M
G PROTEIN STRUCTURE/FUNCTIONR01EY010291 · NEI · VANDERBILT UNIVERSITY · PI HAMM, HEIDI E · 1994 to 2010
$3.9M
GPCR Regulation of insulin secretion by modulation of the release machineryR01DK109204 · NIDDK · VANDERBILT UNIVERSITY · PI HAMM, HEIDI E · 2016 to 2019
$1.4M
Optimization of modulators of Gbg-SNARE interactionR01MH101679 · NIMH · VANDERBILT UNIVERSITY · PI HAMM, HEIDI E, STAUFFER, SHAUN R · 2014 to 2016
$1.2M
Regulation of photoreceptor vesicle resupply and synaptic transfer kineticsF32EY023864 · NEI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI VAN HOOK, MATTHEW JOHN · 2014 to 2015
$113k
CHLORIDE REGULATION OF PHOTORECEPTOR NEUROTRANSMISSIONR29EY010542 · NEI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI THORESON, WALLACE B · 1996 to 2000
$105k
NEI NIH HHS F32 EY023864NEI NIH HHS R01 EY010291NEI NIH HHS R01 EY010542NEI NIH HHS R29 EY010542NIDDK NIH HHS R01 DK109204NIMH NIH HHS R01 MH101679
6 · The paper itself

Abstract

G-protein βγ subunits (Gβγ) interact with presynaptic proteins and regulate neurotransmitter release downstream of Ca

Indexed as

AmbystomaAnimalsExcitatory Postsynaptic PotentialsFemaleGTP-Binding Protein beta SubunitsGTP-Binding Protein gamma SubunitsMaleReceptors, Metabotropic GlutamateRetinal Cone Photoreceptor CellsRetinal Horizontal CellsSNARE ProteinsSynapsesSynaptic TransmissionG-protein Beta gammaGTP-Binding Protein beta SubunitsGTP-Binding Protein gamma SubunitsReceptors, Metabotropic GlutamateSNARE ProteinsG-protein coupled receptormGluRretinaribbonSNARE complexsynapse

Identifiers

PMID28363980
PMCPMC5413191
OpenAlexW2598844730

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.