Evidence map›Paper›PMID 28363971›Full record

ArticleThe Journal of cell biology2017

The bacterial virulence factors VopL and VopF nucleate actin from the pointed end.

Thomas A Burke, Alyssa J Harker, Roberto Dominguez, David R Kovar

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of cell biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.1field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 30 citations in OpenAlex.

  1. Life science alliance · 2026
    Article
  2. Article
  3. Article
  4. Effects of Bile on PathogenicBiomolecules · 2025
    Article
  5. VopX, a novelmBio · 2025
    Article
  6. Article
  7. Review
  8. Antagonistic effects of actin-specific toxins onbioRxiv : the preprint server for biology · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Membrane-dependent actin polymerization mediated by thebioRxiv : the preprint server for biology · 2023
    Article
  15. Article
  16. Review
  17. Review
  18. Celebrating 20 years of live single-actin-filament studies with five golden rules.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Thomas A BurkeDepartment of Molecular Genetics and Cell Biology, The University of Chicago, Chicago, IL 60637.
Alyssa J HarkerDepartment of Molecular Genetics and Cell Biology, The University of Chicago, Chicago, IL 60637.
Roberto DominguezDepartment of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
David R KovarDepartment of Molecular Genetics and Cell Biology, The University of Chicago, Chicago, IL 60637 drkovar@uchicago.edu.ORCID 0000-0002-5747-0949
University of Chicago · USUniversity of Pennsylvania · US

Funding

Molecular And Cellular Biology Training ProgramT32GM007183 · NIGMS · UNIVERSITY OF CHICAGO · PI GLICK, BENJAMIN S, RICE, PHOEBE A · 1985 to 2021
$23.9M
Structural-Functional Basis of Actin Cytoskeleton DynamicsR01GM073791 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI DOMINGUEZ, ROBERTO · 2005 to 2025
$7.0M
Mechanisms of Formin-Mediated Actin Filament Assembly - Renewal 01 - ResubmissionR01GM079265 · NIGMS · UNIVERSITY OF CHICAGO · PI KOVAR, DAVID R · 2007 to 2023
$4.5M
NIGMS NIH HHS R01 GM073791NIGMS NIH HHS R01 GM079265NIGMS NIH HHS T32 GM007183
6 · The paper itself

Abstract

VopL and VopF (VopL/F) are tandem WH2-domain actin assembly factors used by infectious

Indexed as

ActinsBacterial ProteinsPolymerizationVibrioVirulence FactorsActinsBacterial ProteinsVirulence Factors

Identifiers

PMID28363971
PMCPMC5412564
OpenAlexW2598284901

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.