Evidence map›Paper›PMID 28363968›Full record

ArticleApplied and environmental microbiology2017

Benign Rabbit Calicivirus in New Zealand.

Leila J Nicholson, Jackie E Mahar, Tanja Strive, Tao Zheng, Edward C Holmes, Vernon K Ward, Janine A Duckworth

Open access · bronzeAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Rabbit hemorrhagic disease virus 2, 2010-2023: a review of global detections and affected species.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2024
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Viruses · 2019
    Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Leila J NicholsonDepartment of Microbiology & Immunology, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand.
Jackie E MaharCommonwealth Scientific and Industrial Research Organisation, Health and Biosecurity, Black Mountain, Canberra, Australian Capital Territory, Australia.
Tanja StriveCommonwealth Scientific and Industrial Research Organisation, Health and Biosecurity, Black Mountain, Canberra, Australian Capital Territory, Australia.
Tao ZhengAgResearch Ltd., Hopkirk Research Institute, Grasslands Research Centre, Palmerston North, New Zealand.
Edward C HolmesMarie Bashir Institute for Infectious Disease and Biosecurity, School of Life and Environmental Sciences and Sydney Medical School, Charles Perkins Centre, The University of Sydney, Sydney, NSW, Australia.ORCID http://orcid.org/0000-0001-9596-3552
Vernon K WardDepartment of Microbiology & Immunology, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand.
Janine A DuckworthWildlife Ecology and Management Group, Landcare Research, Lincoln, New Zealand duckworthj@landcareresearch.co.nz.
Commonwealth Scientific and Industrial Research Organisation · AUUniversity of Canberra · AUAgResearch · NZThe University of Sydney · AUUniversity of Otago · NZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Czech v351 strain of rabbit hemorrhagic disease virus (RHDV1) is used in Australia and New Zealand as a biological control agent for rabbits, which are important and damaging introduced vertebrate pests in these countries. However, nonpathogenic rabbit caliciviruses (RCVs) can provide partial immunological cross-protection against lethal RHDV infection and thus interfere with effective rabbit biocontrol. Antibodies that cross-reacted against RHDV antigens were found in wild rabbits before the release of RHDV1 in New Zealand in 1997, suggesting that nonpathogenic RCVs were already present in New Zealand. The aim of this study was to confirm the presence of nonpathogenic RCV in New Zealand and describe its geographical distribution. RCV and RHDV antibody assays were used to screen serum samples from 350 wild rabbits from 14 locations in New Zealand. The serological survey indicated that both RCV and RHDV are widespread in New Zealand wild rabbits, with antibodies detected in 10 out of 14 and 12 out of 14 populations, respectively. Two closely related RCV strains were identified in the duodenal tissue from a New Zealand wild rabbit (RCV Gore-425A and RCV Gore-425B). Both variants are most closely related to Australian RCV strains, but with 88% nucleotide identity, they are genetically distinct. Phylogenetic analysis revealed that the New Zealand RCV strains fall within the genetic diversity of the Australian RCV isolates, indicating a relatively recent movement of RCVs between Australia and New Zealand.

Indexed as

AnimalsCaliciviridae InfectionsFemaleHemorrhagic Disease Virus, RabbitMaleNew ZealandPhylogenyRabbitsELISArabbitrabbit calicivirusRHDVvirus discovery

Identifiers

PMID28363968
PMCPMC5440710
OpenAlexW2597505960

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.