ArticleRNA (New York, N.Y.)2017
Computational analysis of nascent peptides that induce ribosome stalling and their proteomic distribution in
Article in RNA (New York, N.Y.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 34 citations in OpenAlex.
- A machine learning approach uncovers principles and determinants of eukaryotic ribosome pausing.Science advances · 2024Article
- The tRNA Gm18 methyltransferase TARBP1 promotes hepatocellular carcinoma progression via metabolic reprogramming of glutamine.Cell death and differentiation · 2024Article
- Comprehensive translational profiling and STE AI uncover rapid control of protein biosynthesis during cell stress.Nucleic acids research · 2024Article
- Massively parallel identification of sequence motifs triggering ribosome-associated mRNA quality control.Nucleic acids research · 2024Article
- Article
- A nascent peptide code for translational control of mRNA stability in human cells.Nature communications · 2022Article
- Mitochondrial mRNA localization is governed by translation kinetics and spatial transport.PLoS computational biology · 2022Article
- Quantitative Proteomics Reveals that Hsp90 Inhibition Dynamically Regulates Global Protein Synthesis in Leishmania mexicana.mSystems · 2021Article
- Ribosome Pausing at Inefficient Codons at the End of the Replicase Coding Region Is Important for Hepatitis C Virus Genome Replication.International journal of molecular sciences · 2020Article
- Comparative Analysis of Gene Expression in Virulent and Attenuated Strains of Infectious Bronchitis Virus at Subcodon Resolution.Journal of virology · 2019Article
- Inverted translational control of eukaryotic gene expression by ribosome collisions.PLoS biology · 2019Article
- Protein synthesis rates and ribosome occupancies reveal determinants of translation elongation rates.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Ribosome profiling analysis of eEF3-depleted Saccharomyces cerevisiae.Scientific reports · 2019Article
- Quantification and discovery of sequence determinants of protein-per-mRNA amount in 29 human tissues.Molecular systems biology · 2019Article
- PausePred and Rfeet: webtools for inferring ribosome pauses and visualizing footprint density from ribosome profiling data.RNA (New York, N.Y.) · 2018Article
- Computational analysis of the oscillatory behavior at the translation level induced by mRNA levels oscillations due to finite intracellular resources.PLoS computational biology · 2018Article
- Pausing of Chloroplast Ribosomes Is Induced by Multiple Features and Is Linked to the Assembly of Photosynthetic Complexes.Plant physiology · 2018Article
- Evolutionary analysis of polyproline motifs in Escherichia coli reveals their regulatory role in translation.PLoS computational biology · 2018Article
- The extent of ribosome queuing in budding yeast.PLoS computational biology · 2018Article
- The impact of ribosomal interference, codon usage, and exit tunnel interactions on translation elongation rate variation.PLoS genetics · 2018Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Interactions between the ribosomal exit tunnel and the nascent peptide can affect translation elongation rates. While previous studies have already demonstrated the feasibility of such interactions, little is known about the nature of the stalling peptide sequences and their distribution in the proteome. Here we ask which peptide sequences tend to occupy the tunnel of stalled ribosomes and how they are distributed in the proteome. Using computational analysis of ribosome profiling data from
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.