Evidence map›Paper›PMID 28363760›Full record

ReviewSeminars in fetal & neonatal medicine2017

Interstitial lung disease in newborns.

Lawrence M Nogee

Open access · greenAbstract readReview
In one paragraph

Review in Seminars in fetal & neonatal medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 101 citations in OpenAlex.

  1. Review
  2. Biallelic LAMP3 variants in 5 families with interstitial lung disease: Evidence of a disease-gene association.Genetics in medicine : official journal of the American College of Medical Genetics · 2026
    Article
  3. Review
  4. Article
  5. Review
  6. Interstitial lung disease in the newborn.Journal of perinatology : official journal of the California Perinatal Association · 2025
    Review
  7. Pediatric Diffuse Lung Disease in Infants: Imaging Findings and Histopathologic Correlation.Radiographics : a review publication of the Radiological Society of North America, Inc · 2024
    Review
  8. Article
  9. A promoterless AAV6.2FF-based lung gene editing platform for the correction of surfactant protein B deficiency.Molecular therapy : the journal of the American Society of Gene Therapy · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Molecular Function and Contribution ofAmerican journal of respiratory and critical care medicine · 2023
    Review
  14. Diagnostic workup of childhood interstitial lung disease.European respiratory review : an official journal of the European Respiratory Society · 2023
    Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Lawrence M NogeeEudowood Neonatal Pulmonary Division, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address: lnogee@jhmi.edu.
Johns Hopkins Medicine · US

Funding

Editing Alveolar Progenitor Cells for Correction of Monogenic DiseaseU01HL134745 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI KOTTON, DARRELL N., MORRISEY, EDWARD E · 2016 to 2022
$8.3M
NHLBI NIH HHS U01 HL134745
6 · The paper itself

Abstract

The term 'interstitial lung disease' (ILD) refers to a group of disorders involving both the airspaces and tissue compartments of the lung, and these disorders are more accurately termed diffuse lung diseases. Although rare, they are associated with significant morbidity and mortality, with the prognosis depending upon the specific diagnosis. The major categories of ILD in children that present in the neonatal period include developmental disorders, growth disorders, surfactant dysfunction disorders, and specific conditions of unknown etiology unique to infancy. Whereas lung histopathology has been the gold standard for the diagnosis of ILD, as many of the disorders have a genetic basis, non-invasive diagnosis is feasible, and characteristic clinical and imaging features may allow for specific diagnosis in some circumstances. The underlying mechanisms, clinical, imaging, and lung pathology features and outcomes of ILD presenting in newborns are reviewed with an emphasis on genetic mechanisms and diagnosis.

Indexed as

ATP-Binding Cassette TransportersCombined Modality TherapyDiagnosis, DifferentialForkhead Transcription FactorsHumansInfant, NewbornLung Diseases, InterstitialMutationPractice Guidelines as TopicPrognosisPulmonary Alveolar ProteinosisReceptor, Fibroblast Growth Factor, Type 2T-Box Domain ProteinsABCA3 protein, humanATP-Binding Cassette TransportersFGFR2 protein, humanForkhead Transcription FactorsFOXF1 protein, humanReceptor, Fibroblast Growth Factor, Type 2T-Box Domain ProteinsTBX4 protein, humanAlveolar capillary dysplasiaGenetic basis of diseaseLung developmentMutationNeuroendocrine cell hyperplasia of infancySurfactant

Identifiers

PMID28363760
PMCPMC5537026
OpenAlexW2598616858

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.