ReviewTrends in cognitive sciences2017
A Network Model of the Emotional Brain.
Review in Trends in cognitive sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06336057 (Mentalizating in Adults Suffering from Narcolepsy Type 1, a Comparative Prospective Study.), which is not on this map. Cited by 190 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Mentalizating in Adults Suffering from Narcolepsy Type 1, a Comparative Prospective Study.
Who cites it
190 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- The effects of childhood adversity: Two specific neural patterns.Neuroscience and biobehavioral reviews · 2025Pooled it
- Hippocampus long-axis specialization throughout development: A meta-analysis.Human brain mapping · 2023Pooled it
- Networks underpinning emotion: A systematic review and synthesis of functional and effective connectivity.NeuroImage · 2021Pooled it
- Emotional Processing in Obsessive-Compulsive Disorder: A Systematic Review and Meta-analysis of 25 Functional Neuroimaging Studies.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2018Pooled it
- Oxytocin Reduces Subjective Fear in Naturalistic Social Contexts via Enhancing Top-Down Middle Cingulate Amygdala Regulation and Brain-Wide Fear Representations.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Trial
- Immersive Virtual Reality eHealth Intervention to Reduce Anxiety and Depression in Pregnant Women: Randomized Controlled Trial.JMIR human factors · 2025Trial
- Predicting pediatric anxiety from the temporal pole using neural responses to emotional faces.Scientific reports · 2021Trial
- A mind-body lifestyle intervention enhances emotional control in patients with major depressive disorder: a randomized, controlled study.Cognitive, affective & behavioral neuroscience · 2020Trial
- Fear-EEG-AI: A Conceptual and Operational Framework for Designing EEG-AI Systems for the Inference of Fear-Compatible Neurophysiological States.Sensors (Basel, Switzerland) · 2026Article
- Examination of poverty trajectories and brain volume as predictors of adolescent depression.Journal of research on adolescence : the official journal of the Society for Research on Adolescence · 2026Article
- Dynamic fMRI networks of human emotion.eLife · 2026Article
- Psychobiological Correlates of Instructed Deceptive Responding: An Exploratory EEG Study.Behavioral sciences (Basel, Switzerland) · 2026Article
- Hierarchical structural-functional coupling reorganization after acute sleep deprivation: Links to spatial working memory and lateralization.Cognitive, affective & behavioral neuroscience · 2026Article
- Developmental linearization of functional connectivity and its alteration in males with autism spectrum disorder.Developmental cognitive neuroscience · 2026Article
- Mapping Depression Correlated Amygdala Communication.Brain topography · 2026Article
- Emotional scars: limbic brain processing alterations in adults with childhood abuse across mental health disorders.Molecular psychiatry · 2026Article
- Exploration of the Interplay Between Trait Emotional Intelligence Dimensions and Creative Potential in Childhood.Behavioral sciences (Basel, Switzerland) · 2026Article
- Psychosocial Health Following Non-Invasive Brain Stimulation of Oculomotor Regions.Behavioral sciences (Basel, Switzerland) · 2026Article
- Contributions of the basolateral amygdala and nucleus accumbens to sustaining not just initiating cognitive effort.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Altered functional connectivity of the hippocampus in cortico-subcortical networks in early-stage and emerging psychosis.European archives of psychiatry and clinical neuroscience · 2026Article
130 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
Emotion is often understood in terms of a circumscribed set of cortical and subcortical brain regions. I propose, instead, that emotion should be understood in terms of large-scale network interactions spanning the entire neuroaxis. I describe multiple anatomical and functional principles of brain organization that lead to the concept of 'functionally integrated systems', cortical-subcortical systems that anchor the organization of emotion in the brain. The proposal is illustrated by describing the cortex-amygdala integrated system and how it intersects with systems involving the ventral striatum/accumbens, septum, hippocampus, hypothalamus, and brainstem. The important role of the thalamus is also highlighted. Overall, the model clarifies why the impact of emotion is wide-ranging, and how emotion is interlocked with perception, cognition, motivation, and action.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.