Evidence map›Paper›PMID 28363527›Full record

Observational studyThe Journal of allergy and clinical immunology2017

Elevated levels of soluble humanleukocyte antigen-G in the airways are a marker for a low-inflammatory endotype of asthma.

Steven R White, Jessie Nicodemus-Johnson, Bharathi Laxman, Darcy R Denner, Edward T Naureckas, D Kyle Hogarth, Randi Stern, Alexa Minc, Julian Solway, Anne Sperling and 1 more

Abstract readLetterObservational Study
In one paragraph

Observational study in The Journal of allergy and clinical immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Journal of clinical medicine · 2023
    Article
  3. Article
  4. Article
  5. DNA methylation signatures in airway cells from adult children of asthmatic mothers reflect subtypes of severe asthma.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  6. Review
  7. Article
  8. Article
  9. Observational
  10. Frontiers in immunology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Steven R WhiteDepartment of Medicine, University of Chicago, Chicago, Ill. Electronic address: swhite@bsd.uchicago.edu.
Jessie Nicodemus-JohnsonDepartment of Human Genetics, University of Chicago, Chicago, Ill.
Bharathi LaxmanDepartment of Medicine, University of Chicago, Chicago, Ill.
Darcy R DennerDepartment of Medicine, University of Chicago, Chicago, Ill.
Edward T NaureckasDepartment of Medicine, University of Chicago, Chicago, Ill.
D Kyle HogarthDepartment of Medicine, University of Chicago, Chicago, Ill.
Randi SternDepartment of Medicine, University of Chicago, Chicago, Ill.
Alexa MincDepartment of Medicine, University of Chicago, Chicago, Ill.
Julian SolwayDepartment of Medicine, University of Chicago, Chicago, Ill.
Anne SperlingDepartment of Medicine, University of Chicago, Chicago, Ill.
Carole OberDepartment of Human Genetics, University of Chicago, Chicago, Ill.

Funding

Re-Engineering Translational Research at the University of ChicagoUL1TR000430 · NCATS · UNIVERSITY OF CHICAGO · PI SOLWAY, JULIAN · 2012 to 2016
$20.2M
RESEARCH TRAINING IN RESPIRATORY BIOLOGYT32HL007605 · NHLBI · UNIVERSITY OF CHICAGO · PI Yun Fang, Gokhan M. Mutlu · 1985 to 2026
$18.1M
Regulation and expression of HLA-G in asthmatic airwaysU19AI095230 · NIAID · UNIVERSITY OF CHICAGO · PI OBER, CAROLE, WHITE, STEVEN R · 2011 to 2016
$10.5M
Summer Program to Increase Heart, Lung, and Blood Biomedical ResearchR25HL096383 · NHLBI · UNIVERSITY OF CHICAGO · PI CHRISTOPHER O OLOPADE, William F Parker · 2009 to 2026
$2.1M
NCATS NIH HHS UL1 TR000430NHLBI NIH HHS R25 HL096383NHLBI NIH HHS T32 HL007605NIAID NIH HHS U19 AI095230
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultAsthmaBiomarkersBronchoalveolar Lavage FluidEosinophilsFemaleHLA-G AntigensHumansImmunoglobulin EMaleMiddle AgedNitric OxideBiomarkersHLA-G AntigensImmunoglobulin ENitric Oxide

Identifiers

PMID28363527
PMCPMC5591772

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.