Evidence map›Paper›PMID 28363360›Full record

ArticleAnales de pediatria (Barcelona, Spain : 2003)2017

[A prospective study to assess the burden of influenza-related hospitalizations and emergency department visits among children in Bilbao, Spain (2010-2011)].

Naiara Ortiz-Lana, Elisa Garrote, Javier Arístegui, Joseba Rementeria, Juan-Antonio García-Martínez, Cynthia McCoig, Pilar García-Corbeira, Raghavendra Devadiga, Mónica Tafalla

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Anales de pediatria (Barcelona, Spain : 2003), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01592799 (Burden of Influenza-related Hospitalizations and Emergency Room Visits in Children in Spain), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01592799 nacompletednot on this map

Burden of Influenza-related Hospitalizations and Emergency Room Visits in Children in Spain

TypeinterventionalSponsorGlaxoSmithKlineRan2010 to 2011Enrolled501ConditionsInfluenzaArmsThroat swab and/or nasopharyngeal swab, Data collection
3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 5 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Naiara Ortiz-LanaDepartamento de Pediatría, Hospital Universitario de Basurto, Universidad del País Vasco (UPV/EHU), Bilbao, España.
Elisa GarroteDepartamento de Pediatría, Hospital Universitario de Basurto, Universidad del País Vasco (UPV/EHU), Bilbao, España. Electronic address: mariaisabel.garrotellanos@osakidetza.net.
Javier ArísteguiDepartamento de Pediatría, Hospital Universitario de Basurto, Universidad del País Vasco (UPV/EHU), Bilbao, España.
Joseba RementeriaDepartamento de Pediatría, Hospital Universitario de Basurto, Universidad del País Vasco (UPV/EHU), Bilbao, España.
Juan-Antonio García-MartínezDepartamento Médico, GSK, Tres Cantos (Madrid), España.
Cynthia McCoigDepartamento Médico, GSK, Tres Cantos (Madrid), España.
Pilar García-CorbeiraDepartamento Médico, GSK, Tres Cantos (Madrid), España.
Raghavendra DevadigaCDOC-B, GSK, Bangalore, India.
Mónica TafallaGSK, Wavre, Bélgica.
Hospital de Basurto · ESUniversity of the Basque Country · ESBangalore Diabetes Centre · INGlaxoSmithKline (Belgium) · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThis study was undertaken to estimate the burden of morbidity associated with laboratory-confirmed influenza in children below 15 years of age. PATIENTS AND

methodsChildren presenting with acute respiratory infection and/or isolated fever at the Basurto University Hospital, Bilbao, Spain between November 2010 and May 2011 were included in this study (NCT01592799). Two nasopharyngeal secretion samples were taken from each; one for a rapid influenza diagnostic test in the emergency department, and the second for laboratory analysis using real-time polymerase chain reaction and viral culture.

resultsA total of 501 children were recruited, of whom 91 were hospitalized. Influenza diagnosis was confirmed in 131 children (26.1%); 120 of 410 (29.3%) treated as outpatients and 11 of 91 (12.1%) hospitalized children. A total of 370 of 501 children (73.9%) had no laboratory test positive for influenza. The proportion of subjects with other respiratory viruses was 145/501 (28.9%) cases and co-infection with the influenza virus plus another respiratory virus was detected in 7/501 (1.4%) cases. Influenza virus types were: A (H1N1 and H3N2) 53.2% (67/126); B (Victoria and Yamagata) 46.0% (58/126); A+B 0.8% (1/126). The median direct medical costs associated with each case of laboratory-confirmed influenza was €177.00 (N=131). No significant differences were observed between the medical costs associated with influenza A and B.

conclusionAlmost half of the cases were influenza virus B type. The administration of a vaccine containing influenza A and B types to children below 15 years of age might reduce the overall burden of the illness.

Indexed as

AdolescentChildChild, PreschoolCost of IllnessEmergency Service, HospitalFemaleHospitalizationHumansInfantInfant, NewbornInfluenza, HumanMaleProspective StudiesSpainTime FactorsEmergency departmentEspañaGripeHospitalizaciónHospitalizationInfluenzaServicio de UrgenciaSpain

Identifiers

PMID28363360
PMCPMC7105034
OpenAlexW2601338128

What OpenQuestion holds

Textmetadata
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.