Evidence map›Paper›PMID 28363321›Full record

Observational studyDrug and alcohol dependence2017

Buprenorphine physician supply: Relationship with state-level prescription opioid mortality.

Hannah K Knudsen, Jennifer R Havens, Michelle R Lofwall, Jamie L Studts, Sharon L Walsh

Open access · hybridAbstract readComparative StudyObservational Study
In one paragraph

Observational study in Drug and alcohol dependence, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
5.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 37 citations in OpenAlex.

  1. Prescribers' satisfaction with delivering medications for opioid use disorder.Substance abuse treatment, prevention, and policy · 2021
    Trial
  2. Physicians' satisfaction with providing buprenorphine treatment.Addiction science & clinical practice · 2019
    Trial
  3. Article
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  12. The HEALing (Helping to End Addiction Long-termDrug and alcohol dependence · 2020
    Article
  13. Review
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  16. Article
  17. Observational
  18. Article
  19. Opioid Prescribing and Physician Autonomy: A Quality of Care Perspective.HSS journal : the musculoskeletal journal of Hospital for Special Surgery · 2019
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Hannah K KnudsenDepartment of Behavioral Science and Center on Drug and Alcohol Research, University of Kentucky, 845 Angliana Avenue, Room 204, Lexington, KY 40508, USA. Electronic address: hannah.knudsen@uky.edu.
Jennifer R HavensDepartment of Behavioral Science and Center on Drug and Alcohol Research, University of Kentucky, 845 Angliana Avenue, Room 201, Lexington, KY 40508, USA. Electronic address: jennifer.havens@uky.edu.
Michelle R LofwallDepartment of Behavioral Science and Center on Drug and Alcohol Research, University of Kentucky, 845 Angliana Avenue, Room 203 Lexington, KY 40508, USA. Electronic address: michelle.lofwall@uky.edu.
Jamie L StudtsDepartment of Behavioral Science, University of Kentucky, 127 Medical Behavioral Science Building, Lexington, KY 40536-0086, USA. Electronic address: jamie.studts@uky.edu.
Sharon L WalshDepartment of Behavioral Science and Center on Drug and Alcohol Research, University of Kentucky, 845 Angliana Avenue, Room 202, Lexington, KY 40508, USA. Electronic address: sharon.walsh@uky.edu.
University of Kentucky · US

Funding

Kentucky Center for Clinical and Translational ScienceUL1TR000117 · NCATS · UNIVERSITY OF KENTUCKY · PI KERN, PHILIP A · 2012 to 2015
$13.3M
Buprenorphine Treatment and Health Reform: Availability, Utilization, and QualityR33DA035641 · NIDA · UNIVERSITY OF KENTUCKY · PI KNUDSEN, HANNAH · 2014 to 2017
$2.0M
NCATS NIH HHS UL1 TR000117NIDA NIH HHS R33 DA035641
6 · The paper itself

Abstract

backgroundBuprenorphine is an effective treatment for opioid use disorder but the supply of buprenorphine physicians is currently inadequate to address the nation's prescription opioid crisis. Perception of need due to rising opioid overdose rates is one possible reason for physicians to adopt buprenorphine. This study examined associations between rates of growth in buprenorphine physicians and prescription opioid overdose mortality rates in US states.

methodsThe total buprenorphine physician supply and number of physicians approved to treat 100 patients (per 100,000 population) were measured from June 2013 to January 2016. States were divided into two groups: those with rates of prescription opioid overdose mortality in 2013 at or above the median (>5.5 deaths per 100,000 population) and those with rates below the median. State-level growth curves were estimated using mixed-effects regression to compare rates of growth between high and low overdose states.

resultsThe total supply and the supply of 100-patient buprenorphine physicians grew significantly (total supply from 7.7 to 9.9 per 100,000 population, p<0.001; 100-patient supply from 2.2 to 3.4 per 100,000 population, p<0.001). Rates of growth were significantly greater in high overdose states when compared to low overdose states (total supply b=0.033, p<0.01; 100-patient b=0.022, p<0.01).

conclusionsThe magnitude of the US prescription opioid crisis, as measured by the rate of prescription opioid overdose mortality, is associated with growth in the number of buprenorphine physicians. Because this observational design cannot establish causality, further research is needed to elucidate the factors influencing physicians' decisions to begin prescribing buprenorphine.

Indexed as

AdultAgedAnalgesics, OpioidBuprenorphineDrug OverdoseFemaleHumansMaleMiddle AgedOpioid-Related DisordersPhysiciansStatistics as TopicUnited StatesYoung AdultAnalgesics, OpioidBuprenorphineBuprenorphinePhysiciansPrescription opioid overdoseTreatment supply

Identifiers

PMID28363321
PMCPMC5584581
OpenAlexW2598075248

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.