Evidence map›Paper›PMID 28363301›Full record

ReviewHand clinics2017

Heterotopic Ossification Following Upper Extremity Injury.

Shailesh Agarwal, Shawn Loder, Benjamin Levi

Registry-linked trialAbstract readReview
In one paragraph

Review in Hand clinics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05547867 (Elbow Heterotopic Ossifications Associated With Radial Head Prosthesis), which is not on this map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05547867 unknown statusnot on this mapstarted 2022, after this paper: background citation

Elbow Heterotopic Ossifications Associated With Radial Head Prosthesis: Risk and Prognostic Factors

TypeobservationalSponsorFundació Institut de Recerca de l'Hospital de la Santa Creu i Sant PauRan2022 to 2024Enrolled60ConditionsRadial Head FractureArmsRadial head prosthesis
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. How to approach Monteggia-like lesions in adults: A review.Annals of medicine and surgery (2012) · 2018
    Review
  14. Novel preclinical murine model of trauma-induced elbow stiffness.Journal of experimental orthopaedics · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Shailesh AgarwalSection of Plastic Surgery, University of Michigan, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA.
Shawn LoderSection of Plastic Surgery, University of Michigan, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA.
Benjamin LeviSection of Plastic Surgery, University of Michigan, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA. Electronic address: blevi@umich.edu.
University of Michigan–Ann Arbor · US

Funding

Novel Pathway and Prevention Strategy for Heterotopic OssificationK08GM109105 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LEVI, BENJAMIN · 2014 to 2017
$785k
Targeting Inflammation and BMP Signaling in Osteoprogenitor Cells of Heterotopic OssificationF32AR066499 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI AGARWAL, SHAILESH · 2015 to 2015
$54k
NIAMS NIH HHS F32 AR066499NIGMS NIH HHS K08 GM109105
6 · The paper itself

Abstract

Heterotopic ossification (HO) presents a substantial barrier to rehabilitation for patients with severe burns or trauma. Although surgical excision is a mainstay of management for this condition, this is unable to address the chronic sequelae of HO, including chronic pain, joint contractures, nerve dysfunction, and open wounds. Current therapeutic modalities are aimed at excision and the prevention of recurrence using nonsteroidal antiinflammatory drugs (NSAIDs) or radiation therapy. Research is now focused on identifying alternative strategies to prevent the initial occurrence of HO through NSAIDs and novel inhibitors of the bone morphogenetic protein signaling pathway.

Indexed as

Arm InjuriesBurnsContractureElbow JointHumansJoint DislocationsOssification, HeterotopicRange of Motion, ArticularBurn injuryElbowHeterotopic ossificationUpper extremity

Identifiers

PMID28363301
PMCPMC5394800
OpenAlexW2604235674

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.