Evidence map›Paper›PMID 28363027›Full record

ReviewAnalytical chemistry2017

Exchange Phenomena in the Electron Paramagnetic Resonance Spectra of the Nitroxyl and Trityl Radicals: Multifunctional Spectroscopy and Imaging of Local Chemical Microenvironment.

Valery V Khramtsov, Andrey A Bobko, Mark Tseytlin, Benoit Driesschaert

Abstract readReview
In one paragraph

Review in Analytical chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Reconfigurable animal bed-EPR resonator assembly for multimodal co-registration.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
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  11. A newJournal of magnetic resonance (San Diego, Calif. : 1997) · 2023
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. EPR Everywhere.Applied magnetic resonance · 2021
    Review
  18. Article
  19. Microsecond Exchange Processes Studied by Two-Dimensional ESR at 95 GHz.Journal of the American Chemical Society · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Valery V KhramtsovIn Vivo Multifunctional Magnetic Resonance center, Robert C. Byrd Health Sciences Center, West Virginia University , Morgantown, West Virginia 26506, United States.ORCID 0000-0001-6187-5546
Andrey A BobkoIn Vivo Multifunctional Magnetic Resonance center, Robert C. Byrd Health Sciences Center, West Virginia University , Morgantown, West Virginia 26506, United States.
Mark TseytlinIn Vivo Multifunctional Magnetic Resonance center, Robert C. Byrd Health Sciences Center, West Virginia University , Morgantown, West Virginia 26506, United States.
Benoit DriesschaertIn Vivo Multifunctional Magnetic Resonance center, Robert C. Byrd Health Sciences Center, West Virginia University , Morgantown, West Virginia 26506, United States.

Funding

West Virginia IDEA-CTRU54GM104942 · NIGMS · WEST VIRGINIA UNIVERSITY · PI Sally Lynn Hodder · 2012 to 2026
$81.0M
In vivo monitoring of tumor microenvironment regulation for macrophagesR01CA194013 · NCI · WEST VIRGINIA UNIVERSITY · PI Timothy D Eubank, Valery V Khramtsov · 2015 to 2026
$3.5M
Profiling chemical tumor microenvironment: Application for diagnostics & therapyR01CA192064 · NCI · WEST VIRGINIA UNIVERSITY · PI EUBANK, TIMOTHY D, KHRAMTSOV, VALERY V · 2015 to 2024
$3.4M
Multifunctional in Vivo EPR Imaging of Tumor MicroenvironmentR21EB022775 · NIBIB · WEST VIRGINIA UNIVERSITY · PI TSEYTLIN, MARK · 2016 to 2017
$427k
NCI NIH HHS R01 CA192064NCI NIH HHS R01 CA194013NIBIB NIH HHS R21 EB022775NIGMS NIH HHS U54 GM104942
6 · The paper itself

Abstract

This Feature overviews the basic principles of using stable organic radicals involved in reversible exchange processes as functional paramagnetic probes. We demonstrate that these probes in combination with electron paramagnetic resonance (EPR)-based spectroscopy and imaging techniques provide analytical tools for quantitative mapping of critical parameters of local chemical microenvironment. The Feature is written to be understandable to people who are laymen to the EPR field in anticipation of future progress and broad application of these tools in biological systems, especially in vivo, over the next years.

Indexed as

AnimalsCellular MicroenvironmentElectron Spin Resonance SpectroscopyFree RadicalsNitrogen OxidesTriphenylmethyl CompoundsFree RadicalsNitrogen OxidesnitroxylTriphenylmethyl Compounds

Identifiers

PMID28363027
PMCPMC5513151

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.