ArticleNeurosurgery2017
Concomitant Primary CNS Lymphoma and FSH-Pituitary Adenoma Arising Within the Sella. Entirely Coincidental?
Article in Neurosurgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- Primary Pituitary Lymphoma in Immunocompetent Patients: A Report on Two Case Studies and the Review of Literature.Frontiers in endocrinology · 2020Pooled it
- Collision tumors at the skull base: unveiling a somatotroph pituitary adenoma coexisting with a petroclival meningioma. Illustrative case.Journal of neurosurgery. Case lessons · 2026Article
- Pituitary T-lymphoblastic lymphoma combined with pituitary adenoma: a rare case report.Frontiers in oncology · 2026Article
- Intracranial primary collision tumours: A comprehensive systematic review on preoperative radiological accuracy and neuro-oncological insights.Brain & spine · 2026Article
- Article
- Case report: Spindle cell sarcoma and pituitary adenoma in the sella region-a rare collision tumor.Frontiers in oncology · 2024Article
- Pituitary lymphoma appearing 9 years after pituitary adenoma resection.Surgical neurology international · 2024Article
- Pituitary Adenoma Coexistent with Sellar Clear Cell Meningioma Unattached to the Dura: Case Report and Treatment Considerations.Journal of neurological surgery reports · 2024Article
- Primary Central Nervous System Lymphoma Mimicking the Presentation of Pituitary Apoplexy: A Case Report.Cureus · 2023Article
- Coexistence of Pituitary Adenoma and Primary Pituitary Lymphoma: A Case Report and Review of the Literature.Frontiers in surgery · 2022Article
- 41-year-old male with a pituitary mass.Brain pathology (Zurich, Switzerland) · 2021Article
- Cushing's disease due to a pituitary adenoma as a component of collision tumor: A case report and review of the literature.Journal of medical case reports · 2020Article
- Primary central nervous system lymphoma involving the hypothalamic-pituitary axis: a case series and pooled analysis.Journal of neuro-oncology · 2020Article
- Accuracy of diffusion-weighted imaging-magnetic resonance in differentiating functional from non-functional pituitary macro-adenoma and classification of tumor consistency.The neuroradiology journal · 2019Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and importanceCollision tumors are the simultaneous occurrence of more than one type of neoplasm within an anatomic space. In the pituitary sella, collision tumors are exceedingly rare, and not much is known about their etiology and prognosis. CLINICAL PRESENTATION: A 74-year-old man presented with a concomitant primary pituitary lymphoma (diffuse large B-cell non-Hodgkin's lymphoma; DLBCL) and follicle-stimulating hormone (FSH)-adenoma diagnosed histologically after clinical features of apoplexy prompted urgent surgical decompression and resection. Strong immunoreactivity for FSH by the lymphoma was evident. Full-body workup demonstrated no other source for the lymphoma. He subsequently underwent 4 cycles of chemotherapy and has been in remission for over 32 months. His ophthalmoplegia at presentation persisted with no further deficits.
conclusionsFour cases of collision tumors of primary pituitary lymphoma and adenoma have previously been reported. This case represents the first combination of an FSH-adenoma and a DLBCL in the literature. Prompt involvement of the hematology-oncology team contributed to the good outcome seen in this case. The putative role played by pituitary hormones in tumorigenesis is reviewed in this case report. The association is either a chance occurrence or due to the induction of lymphoma cell proliferation by the binding of FSH produced by the adenoma to the FSH receptors on the lymphoma cells.
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