Evidence map›Paper›PMID 28362877›Full record

ArticlePLoS computational biology2017

ARACHNE: A neural-neuroglial network builder with remotely controlled parallel computing.

Sergey G Aleksin, Kaiyu Zheng, Dmitri A Rusakov, Leonid P Savtchenko

Open access · goldAbstract read
In one paragraph

Article in PLoS computational biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Equal levels of pre- and postsynaptic potentiation produce unequal outcomes.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024
    Article
  3. Review
  4. Article
  5. Article
  6. Neuron-Glia Interactions and Brain Circuits.Advances in experimental medicine and biology · 2022
    Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Sergey G AleksinAMC Bridge LLC, Waltham MA, United States of America and Dnipro, Ukraine.ORCID 0000-0001-6087-8956
Kaiyu ZhengUCL Institute of Neurology, University College London, London WC1N 3BG, United Kingdom.
Dmitri A RusakovUCL Institute of Neurology, University College London, London WC1N 3BG, United Kingdom.
Leonid P SavtchenkoUCL Institute of Neurology, University College London, London WC1N 3BG, United Kingdom.
University College London · GB

Funding

Medical Research Council G0600368Medical Research Council G0802216Medical Research Council G0900613Wellcome Trust 101896Wellcome Trust 101896/Z/13/Z
6 · The paper itself

Abstract

Creating and running realistic models of neural networks has hitherto been a task for computing professionals rather than experimental neuroscientists. This is mainly because such networks usually engage substantial computational resources, the handling of which requires specific programing skills. Here we put forward a newly developed simulation environment ARACHNE: it enables an investigator to build and explore cellular networks of arbitrary biophysical and architectural complexity using the logic of NEURON and a simple interface on a local computer or a mobile device. The interface can control, through the internet, an optimized computational kernel installed on a remote computer cluster. ARACHNE can combine neuronal (wired) and astroglial (extracellular volume-transmission driven) network types and adopt realistic cell models from the NEURON library. The program and documentation (current version) are available at GitHub repository https://github.com/LeonidSavtchenko/Arachne under the MIT License (MIT).

Indexed as

Models, NeurologicalNeural Networks, ComputerSoftwareCell CommunicationComputational BiologyComputer SimulationHumansNerve NetNeurogliaNeuronsUser-Computer Interface

Identifiers

PMID28362877
PMCPMC5393895
OpenAlexW2601051165

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.