Evidence map›Paper›PMID 28362436›Full record

ReviewNature methods2017

In vivo imaging of neural activity.

Weijian Yang, Rafael Yuste

Open access · greenAbstract readReview
In one paragraph

Review in Nature methods, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 222 papers.

0numbers the graph read from it
0cells of the map it votes in
222citing papers in PubMed
65.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

222 citing papers in PubMed, 433 citations in OpenAlex.

  1. Article
  2. Article
  3. The Importance of Synchrony in the Neural Control of Movement.bioRxiv : the preprint server for biology · 2026
    Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Neurodatascience: Past, Present, and Future.Data science in science · 2026
    Article
  12. In Vivo Wide-Field Fluorescence CaMethods in molecular biology (Clifton, N.J.) · 2026
    Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article

162 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Weijian YangDepartment of Biological Sciences, Neurotechnology Center, Columbia University, New York, New York, USA.
Rafael YusteDepartment of Biological Sciences, Neurotechnology Center, Columbia University, New York, New York, USA.ORCID http://orcid.org/0000-0003-0941-3496
Columbia University · US

Funding

IMAGING FUNCTIONAL CONNECTIVITY IN VISUAL CORTEXR01EY011787 · NEI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI YUSTE, RAFAEL · 1998 to 2021
$6.4M
Functional connectomics of the neocortical microcircuitDP1EY024503 · NEI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI YUSTE, RAFAEL · 2013 to 2017
$4.0M
Functional consequences of GABAergic inhibition of dendritic spines at pubertyR01MH100561 · NIMH · SUNY DOWNSTATE MEDICAL CENTER · PI SMITH, SHERYL S · 2013 to 2017
$3.0M
Two-photon optical control of astrocytic functionR01MH101218 · NIMH · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI YUSTE, RAFAEL · 2013 to 2017
$2.0M
NEI NIH HHS DP1 EY024503NEI NIH HHS R01 EY011787NIMH NIH HHS R01 MH100561NIMH NIH HHS R01 MH101218
6 · The paper itself

Abstract

Since the introduction of calcium imaging to monitor neuronal activity with single-cell resolution, optical imaging methods have revolutionized neuroscience by enabling systematic recordings of neuronal circuits in living animals. The plethora of methods for functional neural imaging can be daunting to the nonexpert to navigate. Here we review advanced microscopy techniques for in vivo functional imaging and offer guidelines for which technologies are best suited for particular applications.

Indexed as

AnimalsBrainCalciumEquipment DesignHumansMicroscopyMicroscopy, FluorescenceMolecular ImagingNeuronsCalcium

Identifiers

PMID28362436
PMCPMC5903578
OpenAlexW2603409505

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.