Evidence map›Paper›PMID 28362258›Full record

ArticleeLife2017

A CDC25 family protein phosphatase gates cargo recognition by the Vps26 retromer subunit.

Tie-Zhong Cui, Tabitha A Peterson, Christopher G Burd

Open access · goldAbstract read
In one paragraph

Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Receptor Recycling by Retromer.Molecular and cellular biology · 2023
    Review
  2. Article
  3. Chitin Synthesis in Yeast: A Matter of Trafficking.International journal of molecular sciences · 2022
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Tie-Zhong CuiDepartment of Cell Biology, Yale School of Medicine, New Haven, United States.
Tabitha A PetersonDepartment of Molecular Physiology and Biophysics, University of Iowa, Iowa City, United States.ORCID 0000-0003-0780-5795
Christopher G BurdDepartment of Cell Biology, Yale School of Medicine, New Haven, United States.ORCID 0000-0003-1831-8706
Yale University · USUniversity of Iowa · US

Funding

TRAFFICKING BY FYVE DOMAIN EFFECTORS OF PI3 KINASER01GM061221 · NIGMS · YALE UNIVERSITY · PI BURD, CHRISTOPHER G · 2000 to 2016
$5.2M
NIGMS NIH HHS R01 GM061221
6 · The paper itself

Abstract

We describe a regulatory mechanism that controls the activity of retromer, an evolutionarily conserved sorting device that orchestrates cargo export from the endosome. A spontaneously arising mutation that activates the yeast (

Indexed as

Gene Expression Regulation, EnzymologicGene Expression Regulation, FungalProtein Processing, Post-TranslationalMutation, MissensePhosphoprotein PhosphatasesPhosphorylationProtein Bindingras-GRF1Saccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsVesicular Transport ProteinsCDC25 protein, S cerevisiaePEP8 protein, S cerevisiaePhosphoprotein Phosphatasesras-GRF1Saccharomyces cerevisiae ProteinsVesicular Transport ProteinsarrestinbiochemistryCDC25 protein phosphatasecell biologyendosomeretromer

Identifiers

PMID28362258
PMCPMC5409824
OpenAlexW2602152213

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.