Evidence map›Paper›PMID 28362257›Full record

ArticleeLife2017

Role of D-aminoacyl-tRNA deacylase beyond chiral proofreading as a cellular defense against glycine mischarging by AlaRS.

Komal Ishwar Pawar, Katta Suma, Ayshwarya Seenivasan, Santosh Kumar Kuncha, Satya Brata Routh, Shobha P Kruparani, Rajan Sankaranarayanan

Open access · goldAbstract read
In one paragraph

Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Mammalian Tolerance to Amino Acid Heterochirality.Chembiochem : a European journal of chemical biology · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Distinct localization of chiral proofreaders resolves organellar translation conflict in plants.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Aminoacyl-tRNA synthetases.RNA (New York, N.Y.) · 2020
    Review
  15. Article
  16. The mechanism of β-The Journal of biological chemistry · 2020
    Article
  17. Article
  18. Chiral checkpoints during protein biosynthesis.The Journal of biological chemistry · 2019
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Komal Ishwar PawarCSIR-Centre for Cellular and Molecular Biology, Hyderabad, India.ORCID 0000-0002-1968-9851
Katta SumaCSIR-Centre for Cellular and Molecular Biology, Hyderabad, India.
Ayshwarya SeenivasanCSIR-Centre for Cellular and Molecular Biology, Hyderabad, India.
Santosh Kumar KunchaCSIR-Centre for Cellular and Molecular Biology, Hyderabad, India.
Satya Brata RouthCSIR-Centre for Cellular and Molecular Biology, Hyderabad, India.
Shobha P KruparaniCSIR-Centre for Cellular and Molecular Biology, Hyderabad, India.
Rajan SankaranarayananCSIR-Centre for Cellular and Molecular Biology, Hyderabad, India.ORCID 0000-0003-4524-9953
Centre for Cellular and Molecular Biology · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Strict L-chiral rejection through Gly-

Indexed as

Alanine-tRNA LigaseAminoacyltransferasesEscherichia coliGlycineAlanine-tRNA LigaseAminoacyltransferasesGlycineamino acidsbiochemistrybiophysicschiralityE. coligenetic codestructural biologytranslationtRNA synthetase

Identifiers

PMID28362257
PMCPMC5409826
OpenAlexW2600244711

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.