Evidence map›Paper›PMID 28362256›Full record

ArticleeLife2017

Frequent exchange of the DNA polymerase during bacterial chromosome replication.

Thomas R Beattie, Nitin Kapadia, Emilien Nicolas, Stephan Uphoff, Adam Jm Wollman, Mark C Leake, Rodrigo Reyes-Lamothe

Open access · goldAbstract read
In one paragraph

Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers.

0numbers the graph read from it
0cells of the map it votes in
76citing papers in PubMed
8.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

76 citing papers in PubMed, 136 citations in OpenAlex.

  1. Article
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  7. Article
  8. Genome integrity relies on rapid recycling of DNA Pol III in bacteria.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  9. The RecBC complex protects single-stranded DNA gaps during lesion bypass.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  10. Article
  11. Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article

16 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Thomas R BeattieDepartment of Biology, McGill University, Montreal, Canada.
Nitin KapadiaDepartment of Biology, McGill University, Montreal, Canada.ORCID 0000-0003-4514-7631
Emilien NicolasDepartment of Biochemistry, University of Oxford, Oxford, United Kingdom.
Stephan UphoffDepartment of Biochemistry, University of Oxford, Oxford, United Kingdom.
Adam Jm WollmanBiological Physical Sciences Institute, Departments of Physics and Biology, University of York, Heslington, United Kingdom.
Mark C LeakeBiological Physical Sciences Institute, Departments of Physics and Biology, University of York, Heslington, United Kingdom.
Rodrigo Reyes-LamotheDepartment of Biology, McGill University, Montreal, Canada.ORCID 0000-0002-5330-3481
McGill University · CAUniversity of Oxford · GBUniversity of York · GB

Funding

Biotechnology and Biological Sciences Research Council BB/N006453/1CIHR 142473Medical Research Council MR/K01580X/1
6 · The paper itself

Abstract

The replisome is a multiprotein machine that carries out DNA replication. In

Indexed as

DNA ReplicationChromosomes, BacterialDNA-Directed DNA PolymeraseEscherichia coliMicroscopy, FluorescenceDNA-Directed DNA PolymerasebacteriabiochemistrychromosomesDNA replicationE. coligenesgenome integrityreplisomesingle-molecule microscopy

Identifiers

PMID28362256
PMCPMC5403216
OpenAlexW2602490333

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.