Evidence map›Paper›PMID 28361912›Full record

ArticleScientific reports2017

Polymorphisms of RAD51B are associated with rheumatoid arthritis and erosion in rheumatoid arthritis patients.

Liqiang Zhi, Shuxin Yao, Wenlong Ma, Weijie Zhang, Honggan Chen, Meng Li, Jianbing Ma

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Genome-wide association study of early-onset and late-onset postpartum depression: the IGEDEPP prospective study.European psychiatry : the journal of the Association of European Psychiatrists · 2024
    Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Disease markers · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Liqiang ZhiDepartment of Joint Surgery, Honghui Hospital, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, China.
Shuxin YaoDepartment of Joint Surgery, Honghui Hospital, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, China.
Wenlong MaDepartment of Hip Injury and Disease, Orthopedic Hospital of Henan Province, Qiming South Road No.82, Luoyang, Henan, China.
Weijie ZhangDepartment of Joint Surgery, Honghui Hospital, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, China.
Honggan ChenDepartment of Hip Injury and Disease, Orthopedic Hospital of Henan Province, Qiming South Road No.82, Luoyang, Henan, China.
Meng LiDepartment of Orthopedics, the First Affiliated Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Jianbing MaDepartment of Joint Surgery, Honghui Hospital, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, China.
Xi'an Honghui Hospital · CNLuoyang Orthopedic-Traumatological Hospital of Henan Province · CNFirst Affiliated Hospital of Xi'an Jiaotong University · CNXi'an Jiaotong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rheumatoid arthritis (RA) is a common, chronic autoimmune disease affecting 0.5-1.0% of adults worldwide, including approximately 4.5-5.0 million patients in China. The genetic etiology and pathogenesis of RA have not yet been fully elucidated. Recently, one new RA susceptibility gene (RAD51B) has been identified in Korean and European populations. In this study, we designed a two-stage case-control study to further assess the relationship of common variants in the RAD51B gene with increased risk of RA in a total of 965 RA patients and 2,511 unrelated healthy controls of Han Chinese ancestry. We successfully identified a common variant, rs911263, as being significantly associated with the disease status of RA (P = 4.8 × 10

Indexed as

Genetic Association StudiesGenetic Predisposition to DiseaseAdultAllelesArthritis, RheumatoidChinaDNA-Binding ProteinsEthnicityFemaleGenotypeHumansMaleMiddle AgedPolymorphism, Single NucleotideDNA-Binding ProteinsRAD51B protein, human

Identifiers

PMID28361912
PMCPMC5374468
OpenAlexW2598864810

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.