Evidence map›Paper›PMID 28361518›Full record

ArticleInternational neurourology journal2017

Ketanserin and Naftopidil Enhance the Potentiating Effect of Alpha-Methyl-Serotonin on the Neurally-Induced Contraction of Human Isolated Urinary Bladder Muscle Strips.

Tsuyoshi Hattori, Philippe Lluel, Céline Rouget, Moèz Rekik, Mitsuharu Yoshiyama

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International neurourology journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Tsuyoshi HattoriDepartment of Medical Affairs, Asahi Kasei Pharma Corporation, Tokyo, Japan.ORCID 0000-0001-6425-3945
Philippe LluelDepartment of Pharmacology, UROsphere SAS, Toulouse, France.ORCID 0000-0002-7951-528X
Céline RougetDepartment of Pharmacology, UROsphere SAS, Toulouse, France.ORCID 0000-0002-4053-1151
Moèz RekikDepartment of Pharmacology, UROsphere SAS, Toulouse, France.ORCID 0000-0001-6132-7064
Mitsuharu YoshiyamaDepartment of Urology, University of Yamanashi Graduate School of Medical Science, Chuo, Yamanashi, Japan.ORCID 0000-0001-8695-884X
Unité de Recherche Interdisplinaire Octogone · FRAsahi Kasei (Japan) · JPUniversity of Yamanashi · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this study was to assess the potential involvement of a specific subtype of 5-hydroxytryptamine (5-HT), 5HT

methodsContractile responses to electrical field stimulation (EFS) were examined in human isolated urinary bladder muscle strips. The potentiation of EFS-induced detrusor contraction was examined by adding cumulative concentrations of a 5-HT and 5-HT

results5-HT and α-Me-5-HT potentiated EFS-induced contraction with a maximal effect (E

conclusionsThe potentiating effect of α-Me-5-HT on neurally-induced contraction of human urinary bladder muscle strips was not found to be mediated via any 5-HT

Indexed as

Alpha-1 Adrenergic ReceptorsProstatismSerotonin ReceptorsUnderactive BladderUrinary Bladder Neck Obstruction

Identifiers

PMID28361518
PMCPMC5380824
OpenAlexW2602946161

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.