Evidence map›Paper›PMID 28361507›Full record

ArticleJournal of the International AIDS Society2017

Client uptake of safer conception strategies: implementation outcomes from the Sakh'umndeni Safer Conception Clinic in South Africa.

Sheree R Schwartz, Jean Bassett, Charles B Holmes, Nompumelelo Yende, Rebecca Phofa, Ian Sanne, Annelies Van Rie

Open access · goldAbstract read
In one paragraph

Article in Journal of the International AIDS Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

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  20. Predictors of Safer Conception Practices Among HIV-Infected Women in Northern Nigeria.International journal of health policy and management · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 4 countries.

Sheree R SchwartzDepartment of Epidemiology, Johns Hopkins School of Public Health, Baltimore, MD, USA.
Jean BassettWitkoppen Health and Welfare Centre, Johannesburg, South Africa.
Charles B HolmesCentre for Infectious Disease Research in Zambia, Lusaka, Zambia.
Nompumelelo YendeWitkoppen Health and Welfare Centre, Johannesburg, South Africa.
Rebecca PhofaWitkoppen Health and Welfare Centre, Johannesburg, South Africa.
Ian SanneClinical HIV Research Unit, Department of Medicine, University of the Witwatersrand, Johannesburg, South Africa.
Annelies Van RieDepartment of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Centre for Infectious Disease Research in Zambia · ZMJohns Hopkins University · USUniversity of North Carolina at Chapel Hill · USUniversity of the Witwatersrand · ZA

Funding

Vaccine Response and Immunotherapeutics SWGP30AI094189 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Richard E. Chaisson · 2012 to 2026
$67.0M
Fogarty Global Health Fellows Coordinating CenterR25TW009340 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CHI, BENJAMIN H. · 2012 to 2016
$6.9M
FIC NIH HHS R25 TW009340Fogarty International Center of the National Institutes of Health R25TW009340Johns Hopkins University Center for AIDS P30AI094189NIAID NIH HHS P30 AI094189United States Agency for International Development (USAID) AID-674-1200033
6 · The paper itself

Abstract

introductionImplementation of safer conception services for HIV-affected couples within primary healthcare clinics in resource-limited settings remains limited. We review service utilization and safer conception strategy uptake during the first three years of

methods

resultsOverall 440 individuals utilized the service including 157 couples in which both partners attended (55%) and 126 unaccompanied female partners. Over half of the couples (55%) represented were in serodiscordant/unknown status relationships. Higher economic status and HIV-negative status of the women increased male partner involvement, while HIV-negative status of the men decreased male involvement. Regarding safer conception strategies, uptake of antiretroviral therapy initiation (90%), vaginal self-insemination among partnerships with HIV-negative men (75%) and timed condomless intercourse strategies (48%) were variable, but generally high. Overall uptake of pre-exposure prophylaxis (PrEP) was 23% and was lower among HIV-negative men than women (7% vs. 44%,

conclusionsSafer conception strategies are generally used by clients per recommendations. High uptake of strategies suggests that the proposed combination prevention methods are acceptable to clients and appropriate for scale-up; however, low uptake of PrEP and MMC among HIV-negative men needs improvement. Targeted community-based efforts to reach men unlinked to safer conception services are needed, alongside streamlined approaches for service scale-up within existing HIV and non-HIV service delivery platforms.

Indexed as

FertilizationSafe SexFemaleHIV InfectionsHumansMalePre-Exposure ProphylaxisSexual PartnersSouth AfricaHIV preventionimplementationpre-exposure prophylaxissafer conceptionself-inseminationserodiscordancesub-Saharan Africatimed condomless sex

Identifiers

PMID28361507
PMCPMC5577727
OpenAlexW2606603176

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.