ArticleCancer causes & control : CCC2017
Reproductive factors and incidence of endometrial cancer in U.S. black women.
Article in Cancer causes & control : CCC, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- Age at Menopause and Risk of Developing Endometrial Cancer: A Meta-Analysis.BioMed research international · 2019Pooled it
- Pubertal timing and incident uterine cancer in the Sister Study cohort.International journal of cancer · 2026Article
- Exploring the Functional and Prognostic Significance of miR-217 in Uterine Corpus Endometrial Carcinoma.Current medicinal chemistry · 2026Article
- Magnetic resonance imaging-based radiomics model for preoperative assessment of risk stratification in endometrial cancer.World journal of clinical cases · 2024Article
- A new method that facilitates the diagnosis of endometrial cancer: the ratio of endometrial thickness to the full thickness of the uterine wall and subcutaneous adipose tissue measurements.Przeglad menopauzalny = Menopause review · 2024Article
- The global incidence, mortality, and burden of uterine cancer in 2019 and correlation with SDI, tobacco, dietary risks, and metabolic risk factors: An ecological study.Health science reports · 2024Article
- Article
- Risk factors for endometrial cancer in Black women.Cancer causes & control : CCC · 2023Article
- Socio-economic variations of breast cancer treatment and discontinuation: a study from a public tertiary cancer hospital in Mumbai, India.BMC women's health · 2023Article
- Review of mendelian randomization studies on age at natural menopause.Frontiers in endocrinology · 2023Review
- A prognostic model and immune regulation analysis of uterine corpus endometrial carcinoma based on cellular senescence.Frontiers in oncology · 2022Article
- miR-149-3p Is a Potential Prognosis Biomarker and Correlated with Immune Infiltrates in Uterine Corpus Endometrial Carcinoma.International journal of endocrinology · 2022Article
- Racial/ethnic differences in anthropometric and hormone-related factors and endometrial cancer risk: the Multiethnic Cohort Study.British journal of cancer · 2021Article
- Identification of Tumor Tissue of Origin with RNA-Seq Data and Using Gradient Boosting Strategy.BioMed research international · 2021Article
- Construction of dysregulated long non-coding RNA-associated competing endogenous RNA network in uterine corpus endometrial carcinoma.Translational cancer research · 2020Article
- Long-term effect of pregnancy-related factors on the development of endometrial neoplasia: A nationwide retrospective cohort study.PloS one · 2019Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
purposePrevious studies have shown that reproductive history is a strong determinant of endometrial cancer risk among white women. Less is known about how reproductive history affects endometrial cancer risk among black women, whose incidence and mortality differ from white women. We investigated the associations of age at menarche, parity, timing of births, and menopausal age with endometrial cancer in the Black Women's Health Study, a prospective cohort study.
methodsEvery 2 years from 1995 to 2013, 47,555 participants with intact uteri at baseline in 1995 completed questionnaires on reproductive and medical history, and lifestyle factors. Self-reported cases of endometrial cancer were confirmed by medical record, cancer registry, or death certificate when available. Cox proportional hazards regression was used to estimate multivariable incidence rate ratios (IRR) and 95% confidence intervals (CI).
resultsDuring 689,501 person-years of follow-up, we identified 300 incident cases of endometrial cancer. The strongest associations with endometrial cancer were found for early age at menarche (<11 vs. 12-13 years: IRR 1.82, 95% CI 1.31, 2.52), and later age at first birth (≥30 vs. <20 years: IRR 0.26, 95% CI 0.13, 0.50). Parous women were less likely than nulliparous women to develop endometrial cancer (IRR 0.77, 95% CI 0.57, 1.05), but there was little evidence of a dose-response relationship for number of births.
conclusionAssociations between reproductive factors and endometrial cancer among black women were generally consistent with those in studies of white women.
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