ReviewEndocrine pathology2017
Noninvasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features: Historical Context, Diagnosis, and Future Challenges.
Review in Endocrine pathology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 27 citations in OpenAlex.
- European perspective on the use of molecular tests in the diagnosis and therapy of thyroid neoplasms.Gland surgery · 2020Review
- Revised criteria for diagnosis of NIFTP reveals a better correlation with tumor biological behavior.Endocrine connections · 2019Article
- "Non-invasive Follicular Thyroid Neoplasm with Papillary like Nuclear Features": An Institutional Retrospective Study with Re-nomenclature and Re-classification.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2019Article
- Integrin β4 promotes invasion and anoikis resistance of papillary thyroid carcinoma and is consistently overexpressed in lymphovascular tumor thrombus.Journal of Cancer · 2019Article
- Reclassification as NIFTP: a Retrospective Review in a Single Institution with an Emphasis on Workload.Endocrine pathology · 2018Article
- Management of Low-Risk Papillary Thyroid Cancer.Endocrinology and metabolism (Seoul, Korea) · 2018Review
- Programmed death-ligand 1 expression by digital image analysis advances thyroid cancer diagnosis among encapsulated follicular lesions.Oncotarget · 2018Article
- Long-Term Outcomes of Patients with Noninvasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features (NIFTP) ≥4 cm Treated Without Radioactive Iodine.Endocrine pathology · 2017Article
- Current Advances in Thyroid Cancer Management. Are We Ready for the Epidemic Rise of Diagnoses?International journal of molecular sciences · 2017Review
- Molecular Profiling of Follicular Variant of Papillary Thyroid Cancer Reveals Low-Risk Noninvasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features: A Paradigm Shift to Reduce Aggressive Treatment of Indolent Tumors.Indian journal of endocrinology and metabolismArticle
Corrections and comments
- Retraction · 2018-08-07Duplication of/in Article ·
- Retracted
Authors and funding
3 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The encapsulated/well-demarcated non-invasive form of follicular variant of papillary thyroid carcinoma (FVPTC) that occurs annually in 45,000 patients worldwide was thought for 30 years to be a carcinoma. Many studies have now shown almost no recurrence in these non-invasive tumors, even in patients treated by surgery without radioactive iodine therapy. The categorization of the tumor as cancer has led to aggressive forms of treatment, with their side effects, financial costs, and the psychological and social impact of a cancer diagnosis. Recently, the encapsulated/well-demarcated non-invasive, FVPTC was renamed as noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) by an international group of experts. The new terminology lacks the carcinoma label enabling clinicians to avoid aggressive therapy. By taking the reader through the history of FVPTC, this article explains how diagnostic criteria for thyroid carcinoma of follicular cells have evolved over the last 60 years. It discusses the steps that led to the labeling of FVPTC as cancer and highlights the various studies that helped reclassify and rename this tumor. It also sheds light on the impact of this reclassification on cytologic diagnosis and focuses on the studies needed to refine and expand the histologic criteria of NIFTP. By understanding the history of this change in nomenclature, future classification of tumors will be greatly improved.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.