ArticleDie Naturwissenschaften2017
Controlling enzymatic activity by immobilization on graphene oxide.
Article in Die Naturwissenschaften, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 47 citations in OpenAlex.
- Advanced Technologies for Wastewater Treatment: Graphene-Based Catalysts.Molecules (Basel, Switzerland) · 2025Review
- Advances in the Tribological Performance of Graphene Oxide and Its Composites.Materials (Basel, Switzerland) · 2025Review
- Enzyme graphene oxide interaction: the case system of β-lactamases.RSC advances · 2025Article
- Microbial Immobilized Enzyme Biocatalysts for Multipollutant Mitigation: Harnessing Nature's Toolkit for Environmental Sustainability.International journal of molecular sciences · 2024Review
- Recent Prospects of Carbonaceous Nanomaterials-Based Laccase Biosensor for Electrochemical Detection of Phenolic Compounds.Biosensors · 2023Review
- A Simple Replica Method as the Way to Obtain a Morphologically and Mechanically Bone-like Iron-Based Biodegradable Material.Materials (Basel, Switzerland) · 2022Article
- Determination of Graphene Oxide Adsorption Space by Lysozyme Uptake─Mechanistic Studies.The journal of physical chemistry. B · 2022Article
- Protein Corona Hinders N-CQDs Oxidative Potential and Favors Their Application as Nanobiocatalytic System.International journal of molecular sciences · 2021Article
- A New Approach to Obtaining Nano-Sized Graphene Oxide for Biomedical Applications.Materials (Basel, Switzerland) · 2021Article
- Ciprofloxacin and Graphene Oxide Combination-New Face of a Known Drug.Materials (Basel, Switzerland) · 2020Article
- Congo Red Decolorization Using Textile Filters and Laccase-Based Nanocomposites in Continuous Flow Bioreactors.Nanomaterials (Basel, Switzerland) · 2020Article
- Lipase immobilized on functionalized superparamagnetic few-layer graphene oxide as an efficient nanobiocatalyst for biodiesel production fromBiotechnology for biofuels · 2020Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this study, graphene oxide (GO) has been applied as a matrix for enzyme immobilization. The protein adsorption capacity of GO is much higher than of other large surface area carbonaceous materials. Its structure and physicochemical properties are reported beneficial also for enzymatic activity modifications. The experimental proof was done here that GO-based biocatalytic systems with immobilized catalase are modifiable in terms of catalyzed reaction kinetic constants. It was found that activity and stability of catalase, considered here as model enzyme, closely depend on enzyme/GO ratio. The changes in kinetic parameters can be related to secondary structure alterations. The correlation between enzyme/GO ratio and kinetic and structure parameters is reported for the first time and enables the conscious control of biocatalytic processes and their extended applications. The biological activity of obtained biocatalytic systems was confirmed in vitro by the use of functional test. The addition of immobilized catalase improved the cells' viability after they were exposed to hydrogen peroxide and tert-butyl-hydroperoxide used as source of reactive oxygen species.
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