Evidence map›Paper›PMID 28361299›Full record

ReviewHepatology international2018

Invasive and non-invasive assessment of portal hypertension.

Jonathan Chung-Fai Leung, Thomson Chi-Wang Loong, James Pang, Jeremy Lok Wei, Vincent Wai-Sun Wong

Abstract readReview
PubMed Publisher
In one paragraph

Review in Hepatology international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Article
  2. Endo-Hepatology: Paradigm Shift in Endosonographic Diagnosis for Liver Disease to Digestive Endoscopy.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2026
    Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Does Portal Hypertension Increase the Risk ofJournal of clinical medicine · 2024
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Portal Hypertension as a Complication of Cystic Echinococcosis: A 20-Year Cohort Analysis.The American journal of tropical medicine and hygiene · 2021
    Article
  14. Hepatic Venous Pressure Gradient.Clinical liver disease · 2021
    Review
  15. Review
  16. [Experimental studies for noninvasive assessment of portal vein pressure based on contrast enhanced subharmonic sonographic imaging].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2020
    Article
  17. Noninvasive imaging assessment of portal hypertension.Abdominal radiology (New York) · 2020
    Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jonathan Chung-Fai LeungDepartment of Medicine and Therapeutics, 9/F, Clinical Sciences Building, Prince of Wales Hospital, 30-32 Ngan Shing Street, Shatin, Hong Kong, China.
Thomson Chi-Wang LoongDepartment of Medicine and Therapeutics, 9/F, Clinical Sciences Building, Prince of Wales Hospital, 30-32 Ngan Shing Street, Shatin, Hong Kong, China.
James PangDepartment of Medicine and Therapeutics, 9/F, Clinical Sciences Building, Prince of Wales Hospital, 30-32 Ngan Shing Street, Shatin, Hong Kong, China.
Jeremy Lok WeiDepartment of Medicine and Therapeutics, 9/F, Clinical Sciences Building, Prince of Wales Hospital, 30-32 Ngan Shing Street, Shatin, Hong Kong, China.
Vincent Wai-Sun WongDepartment of Medicine and Therapeutics, 9/F, Clinical Sciences Building, Prince of Wales Hospital, 30-32 Ngan Shing Street, Shatin, Hong Kong, China. wongv@cuhk.edu.hk.ORCID http://orcid.org/0000-0003-2215-9410

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Portal hypertension is the central driver of complications in patients with chronic liver diseases and cirrhosis. The diagnosis of portal hypertension has important prognostic and clinical implications. In particular, screening for varices in patients with portal hypertension can effectively reduce the morbidity and mortality of variceal bleeding. In this article, we review the invasive and non-invasive methods to assess portal hypertension. Hepatic venous pressure gradient remains the gold standard to measure portal pressure but is invasive and seldom performed outside expert centers and research settings. In recent years, a number of non-invasive tests of fibrosis have shown good correlation with liver histology. They also show promise in identifying patients with portal hypertension and large varices. As a result, the latest Baveno VI consensus guidelines endorse the use of liver stiffness measurement by transient elastography and platelet count as initial assessment to select patients for varices screening. On the other hand, the performance of non-invasive tests in assessing the response to non-selective beta-blockers or transjugular intrahepatic portosystemic shunting is either suboptimal or unclear.

Indexed as

Adrenergic beta-AntagonistsBlood Cell CountBlood PlateletsElasticity Imaging TechniquesEsophageal and Gastric VaricesGastrointestinal HemorrhageHumansHypertension, PortalLiverPortal PressurePortasystemic Shunt, Transjugular IntrahepaticPredictive Value of TestsPrognosisAdrenergic beta-AntagonistsBaveno VI criteriaHepatic venous pressure gradientLiver stiffness measurementMagnetic resonance elastographyTransient elastographyVariceal bleeding

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.