Evidence map›Paper›PMID 28361120›Full record

ArticleTransplantation direct2017

Acute Rejection Phenotypes in the Current Era of Immunosuppression: A Single-Center Analysis.

Caroline Wehmeier, Patrizia Amico, Patricia Hirt-Minkowski, Argyrios Georgalis, Gideon Höenger, Thomas Menter, Michael Mihatsch, Felix Burkhalter, Juerg Steiger, Michael Dickenmann and 2 more

Abstract read
In one paragraph

Article in Transplantation direct, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Kidney transplant arteriopathy revisited.Journal of nephrology · 2025
    Article
  2. Article
  3. Review
  4. Proposed Definitions of Antibody-Mediated Rejection for Use as a Clinical Trial Endpoint in Kidney Transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2022
    Article
  5. Short- and long-term impact of neutropenia within the first year after kidney transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2021
    Article
  6. Article
  7. Article
  8. Article
  9. Precision transplant pathology.Current opinion in organ transplantation · 2020
    Review
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Caroline WehmeierClinic for Transplantation Immunology and Nephrology, University Hospital Basel, Basel, Switzerland.
Patrizia AmicoClinic for Transplantation Immunology and Nephrology, University Hospital Basel, Basel, Switzerland.
Patricia Hirt-MinkowskiClinic for Transplantation Immunology and Nephrology, University Hospital Basel, Basel, Switzerland.
Argyrios GeorgalisClinic for Transplantation Immunology and Nephrology, University Hospital Basel, Basel, Switzerland.
Gideon HöengerClinic for Transplantation Immunology and Nephrology, University Hospital Basel, Basel, Switzerland.
Thomas MenterInstitute for Pathology, University Hospital Basel, Basel, Switzerland.
Michael MihatschInstitute for Pathology, University Hospital Basel, Basel, Switzerland.
Felix BurkhalterClinic for Transplantation Immunology and Nephrology, University Hospital Basel, Basel, Switzerland.
Juerg SteigerClinic for Transplantation Immunology and Nephrology, University Hospital Basel, Basel, Switzerland.
Michael DickenmannClinic for Transplantation Immunology and Nephrology, University Hospital Basel, Basel, Switzerland.
Helmut HopferInstitute for Pathology, University Hospital Basel, Basel, Switzerland.
Stefan SchaubClinic for Transplantation Immunology and Nephrology, University Hospital Basel, Basel, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBesides 'definitive rejection', the Banff classification includes categories for 'suspicious for rejection' phenotypes. The aim of this study was to determine the frequency and phenotypes of rejection episodes in 316 consecutive renal transplants from 2009 to 2014 grouped into patients without/with pretransplant HLA-DSA (ptDSA

methodsAll adequate indication (n = 125) and surveillance biopsies (n = 538) performed within the first year posttransplant were classified according to the current Banff criteria.

results'Suspicious for rejection' phenotypes were 3 times more common than 'definitive rejection' phenotypes in biopsies from ptDSA

conclusions'Suspicious for rejection' phenotypes are very common in the current era and outnumber the frequency of 'definitive rejection' within the first year posttransplant.

Identifiers

PMID28361120
PMCPMC5367753

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.