Evidence map›Paper›PMID 28360997›Full record

ReviewTranslational neurodegeneration2017

Imaging biomarkers in Parkinson's disease and Parkinsonian syndromes: current and emerging concepts.

Usman Saeed, Jordana Compagnone, Richard I Aviv, Antonio P Strafella, Sandra E Black, Anthony E Lang, Mario Masellis

Abstract readReview
In one paragraph

Review in Translational neurodegeneration, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 98 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
98citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

98 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Multivariate radiomics models based onEuropean journal of nuclear medicine and molecular imaging · 2021
    Trial
  4. Trial
  5. Review
  6. Review
  7. Review
  8. The role of neuro-imaging in multiple system atrophy.Journal of neural transmission (Vienna, Austria : 1996) · 2026
    Review
  9. A case report: Neuroimaging in an atypical presentation of Parkinson's disease.The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa · 2026
    Article
  10. Review
  11. Review
  12. Review
  13. Article
  14. Article
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  17. Article
  18. First-in-human study of D6-[EJNMMI radiopharmacy and chemistry · 2024
    Article
  19. Article
  20. Article

38 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Usman SaeedInstitute of Medical Science, Faculty of Medicine, University of Toronto, Toronto, Canada.
Jordana CompagnoneInstitute of Medical Science, Faculty of Medicine, University of Toronto, Toronto, Canada.
Richard I AvivDepartment of Medical Imaging, University of Toronto and Division of Neuroradiology, Sunnybrook Health Sciences Centre, Toronto, Canada.
Antonio P StrafellaResearch Imaging Centre, Centre for Addiction and Mental Health, Toronto, Canada.
Sandra E BlackInstitute of Medical Science, Faculty of Medicine, University of Toronto, Toronto, Canada.
Anthony E LangDivision of Neurology, Department of Medicine, University of Toronto, Toronto, Canada.
Mario MasellisInstitute of Medical Science, Faculty of Medicine, University of Toronto, Toronto, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Two centuries ago in 1817, James Parkinson provided the first medical description of Parkinson's disease, later refined by Jean-Martin Charcot in the mid-to-late 19th century to include the atypical parkinsonian variants (also termed, Parkinson-plus syndromes). Today, Parkinson's disease represents the second most common neurodegenerative disorder with an estimated global prevalence of over 10 million. Conversely, atypical parkinsonian syndromes encompass a group of relatively heterogeneous disorders that may share some clinical features with Parkinson's disease, but are uncommon distinct clinicopathological diseases. Decades of scientific advancements have vastly improved our understanding of these disorders, including improvements in

Indexed as

Atypical parkinsonian syndromeBiomarkersDiffusion tensor imagingMolecular imagingMRIMyocardial scintigraphyParkinson’s diseasePETSPECTTranscranial sonography

Identifiers

PMID28360997
PMCPMC5370489

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.