Evidence map›Paper›PMID 28360660›Full record

ArticleNoro psikiyatri arsivi2014

The Relationship of Serum S100B Levels with Infarction Size and Clinical Outcome in Acute Ischemic Stroke Patients.

Özlem Selçuk, Vildan Yayla, Murat Çabalar, Vildan Güzel, Samiye Uysal, Asuman Gedikbaşi

Abstract read
In one paragraph

Article in Noro psikiyatri arsivi, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
0.1field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 37 citations in OpenAlex.

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  7. A review of theFrontiers in pharmacology · 2024
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  11. Nutrition and metabolism status alteration in advanced hepatocellular carcinoma patients treated with anti-PD-1 immunotherapy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020
    Article
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  13. The elevation of S100B and downregulation of circulating miR-602 in the sera of ischemic stroke (IS) patients: the emergence of novel diagnostic and prognostic markers.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2020
    Article
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  15. Expression of S100B Protein in Ischemia/Reperfusion-Induced Brain Injury After Cyclosporine Therapy: A Biochemical Serum Marker with Prognostic Value?Medical science monitor : international medical journal of experimental and clinical research · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Özlem SelçukBulanık State Hospital, Neurology Clinics, Muş, Turkey.
Vildan YaylaBakırköy Dr. Sadi Konuk Education and Research Hospital, Neurology Clinics, İstanbul, Turkey.
Murat ÇabalarBakırköy Dr. Sadi Konuk Education and Research Hospital, Neurology Clinics, İstanbul, Turkey.
Vildan GüzelVan Region Training and Research Hospital, Neurology Clinics, Van, Turkey.
Samiye UysalBakırköy Dr. Sadi Konuk Education and Research Hospital, Neurology Clinics, İstanbul, Turkey.
Asuman GedikbaşiBakırköy Dr. Sadi Konuk Education and Research Hospital, Biochemistry Clinics, İstanbul, Turkey.
Bakırköy Dr.Sadi Konuk Eğitim ve Araştırma Hastanesi · TRSivas State Hospital · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionS100B protein, which helps nerve development and differentiation, is produced by astrocytes and can be detected in peripheral circulation after brain damage. In this study, we aimed to investigate the relationship between the serum S100B protein level and the infarction volume and clinical outcome and also the early prognostic role of serum S100B protein in patients with ischemic stroke.

methodFifty patients admitted in the first 24-hour period of acute ischemic stroke were evaluated prospectively, and the findings were compared to those of the controls (n=26). S100B levels of the patients and neurological findings on days 1, 3, and 5 and their functional outcomes on the discharge day and at the first month were recorded by the same examiner.

resultsS100B levels were not affected by sex, age, or concomitant systemic diseases. The maximum levels of S100B were recorded on the 3

conclusionThe detection of high S100B levels in peripheral circulation after acute ischemic stroke and the correlations of S100B levels with infarct size (good) and disability (poor) imply that S100B protein may be used as a peripheral marker in acute ischemic stroke patients.

Indexed as

biological markersBraincerebrovascular disordersprognosis

Identifiers

PMID28360660
PMCPMC5353176
OpenAlexW2334652422

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.