Evidence map›Paper›PMID 28360597›Full record

ArticleNoro psikiyatri arsivi2014

Therapeutic Plasma Exchange in Neurologic Diseases: An Experience with 91 Patients in Seven Years.

Sibel Karaca, İlknur Kozanoğlu, Başak Karakurum Göksel, Mehmet Karataş, Meliha Tan, V Deniz Yerdelen, Semih Giray, Zülfikar Arlier

Open access · greenAbstract read
In one paragraph

Article in Noro psikiyatri arsivi, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Sibel KaracaBaşkent University Faculty of Medicine, Adana Research and Implementation Center, Department of Neurology, Adana, Turkey.
İlknur KozanoğluBaşkent University Faculty of Medicine, Adana Research and Implementation Center, Department of Hematology, Adana, Turkey.
Başak Karakurum GökselBaşkent University Faculty of Medicine, Adana Research and Implementation Center, Department of Neurology, Adana, Turkey.
Mehmet KarataşBaşkent University Faculty of Medicine, Adana Research and Implementation Center, Department of Neurology, Adana, Turkey.
Meliha TanBaşkent University Faculty of Medicine, Adana Research and Implementation Center, Department of Neurology, Adana, Turkey.
V Deniz YerdelenBaşkent University Faculty of Medicine, Adana Research and Implementation Center, Department of Neurology, Adana, Turkey.
Semih GirayBaşkent University Faculty of Medicine, Adana Research and Implementation Center, Department of Neurology, Adana, Turkey.
Zülfikar ArlierBaşkent University Faculty of Medicine, Adana Research and Implementation Center, Department of Neurology, Adana, Turkey.
Başkent University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIn this study, we report the results of our experience of therapeutic plasma exchange (TPE) for neuroimmunologic disorders performed at our hospital over a seven-year period.

methodsWe retrospectively reviewed the medical records of 91 patients (53 male, 38 female) who had been treated at our center with TPE.

results60 patients with Guillain-Barrè syndrome (GBS), 23 with myasthenia gravis (MG), 4 with chronic inflammatory demyelinating polyneuropathy (CIDP) and 1 patient each with polymyositis, septic encephalopathy, acute disseminated encephalomyelitis (ADEM) and Opsoclonus-Myoclonus syndrome (OMS) received TPE. 26.7% of GBS patient's made complete recovery, 61.7% had partial recovery and 11.7% patients died due to respiratory failure. Despite our best efforts and effective TPE treatments, 13.4% of MG patients deceased, however, 78% had full recovery. Three patients with CIDP were discharged with full and 1 patient with partial recovery. The patient with ADEM had partial recovery with TPE at first, but deceased 2 months later due to pneumonia-related respiratory insufficiency. While, patient with polymyositis had slight-partial recovery, we obtained full recovery with TPE in septic encephalopathy and OMS patients. The side effects and complications of treatments with TPE, which included hypotension, hypocalcaemia and anemia, were mild and manageable.

conclusionThe improvement rates were encouraging and we concluded that significant benefit can be achieved with TPE for the treatment of neuroimmunological disorders.

Indexed as

Chronic Inflammatory Demyelinating PolyneuropathyGuillain-Barre syndromeMyasthenia GravisTherapeutic Plasma Exchange

Identifiers

PMID28360597
PMCPMC5370258
OpenAlexW2313724488

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.