Evidence map›Paper›PMID 28360527›Full record

ReviewOncoTargets and therapy2017

Role of cytokines and chemokines in alcohol-induced tumor promotion.

Danlei Chen, Fengyun Zhang, Haifeng Ren, Jia Luo, Siying Wang

Open access · goldAbstract readReview
In one paragraph

Review in OncoTargets and therapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. The elusive Luminal B breast cancer and the mysterious chemokines.Journal of cancer research and clinical oncology · 2023
    Article
  4. Article
  5. Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Danlei ChenSchool of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui, People's Republic of China.
Fengyun ZhangSchool of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui, People's Republic of China.
Haifeng RenSchool of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui, People's Republic of China.
Jia LuoDepartment of Pharmacology and Nutritional Sciences, University of Kentucky, College of Medicine, Lexington, KY, USA.
Siying WangSchool of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui, People's Republic of China.
Anhui Medical University · CNUniversity of Kentucky · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Excessive chronic alcohol consumption has become a worldwide health problem. The oncogenic effect of chronic alcohol consumption is one of the leading concerns. The mechanisms of alcohol-induced tumorigenesis and tumor progression are largely unknown, although many factors have been implicated in the process. This review discusses the recent progress in this research area with concentration on alcohol-induced dysregulation of cytokines and chemokines. Based on the available evidence, we propose that alcohol promotes tumor progression by the dysregulation of the cytokine/chemokine system. In addition, we discuss specific transcription factors and signaling pathways that are involved in the action of these cytokines/chemokines and the oncogenic effect of alcohol. This review provides novel insight into the mechanisms of alcohol-induced tumor promotion.

Indexed as

alcoholchemokinescytokinessignal transductiontherapytranscription factorstumor promotion

Identifiers

PMID28360527
PMCPMC5364014
OpenAlexW2595148556

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.