ArticleJournal of clinical orthopaedics and trauma
Vitamin D status and adult fracture healing.
Article in Journal of clinical orthopaedics and trauma. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed, 60 citations in OpenAlex.
- The efficacy of oral vitamin D supplements on fusion outcome in patients receiving elective lumbar spinal fusion-a randomized control trial.BMC musculoskeletal disorders · 2022Trial
- The Effect of Bolus Vitamin DJournal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2021Trial
- The role and therapeutic potential of vitamins in fracture healing.Nutrition journal · 2026Review
- Parathyroid Hormone in the Management of Pelvic Fragility Fractures: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2026Review
- Low Vitamin D Levels Are Associated With Longer Healing Times in Pediatric Fracture Patients.Journal of the Pediatric Orthopaedic Society of North America · 2026Article
- Vitamin D and Fracture Healing.Advances in experimental medicine and biology · 2026Review
- Review
- Correlation between Vitamin D Levels and Healing Time in Lower Limb Fractures.Journal of orthopaedic case reports · 2025Article
- The impact of surgeons' experience and practice on postoperative cervical collar use after single-level anterior cervical discectomy and fusion: a cross-sectional survey in Heilongjiang province, China.BMC musculoskeletal disorders · 2025Article
- Vitamin D deficiency is associated with adverse medical outcomes following total shoulder arthroplasty.JSES international · 2025Article
- Article
- Pediatric femoral shaft fracture requiring revision surgery for nonunion associated with vitamin D and K deficiencies: a case report.Journal of medical case reports · 2024Article
- Does Serum Vitamin D Influence the Prognosis of Critically Ill Patients with Trauma? A Prospective, Observational Study in a Trauma Center.Clinics in orthopedic surgery · 2023Observational
- Lower 25-hydroxyvitamin D (25OHD) levels, diabetes and age are associated with foot and ankle fracture treatment complications.Archives of endocrinology and metabolism · 2023Article
- Prevalence of inadequate vitamin D level and its predictors in children presenting with torus fractures.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2023Article
- Characterization of vitamin D deficiency and use of a standardized supplementation protocol in orthopaedic trauma patients.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2023Article
- The Effect of Vitamin D Supplementation for Bone Healing in Fracture Patients: A Systematic Review.Advances in orthopedics · 2023Review
- Article
- Varus collapse following anterior closing wedge proximal tibial osteotomy for ACL revision reconstruction: a case series.Journal of experimental orthopaedics · 2022Article
- Bone turnover markers as surrogates of fracture healing after intramedullary fixation of tibia and femur fractures.Bone & joint research · 2022Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe effect of vitamin D on maintaining bone health is well researched and its role in the various metabolic stages of fracture healing has become evident, the clinical effects of a vitamin D deficiency in human fracture healing are less well described. Considering today's high prevalence of vitamin D deficiency, the aim of this present study was to investigate the effect of vitamin D status on human adult fracture healing.
methodsThe serum calcidiol concentration was measured in a cohort of adult patients with a fracture in the upper or lower extremity between September 2012 and October 2013. Deficient patients (serum calcidiol <50 nmol/L) were treated with vitamin D. Clinical and radiological consolidation was determined.
resultsVitamin D concentration was measured in 617 patients; 249 (40%) were vitamin D deficient, they subsequently received vitamin D supplements. In 141 patients with a deficiency vitamin D was measured again after 4 months; 111 patients (78.7%) were no longer vitamin D deficient, and 30 remained vitamin D deficient. In six patients of the entire cohort, a clinical delayed union was described. The incidence of delayed union was higher in the group that remained vitamin D deficient (9.7%) compared to the patients who were not initially deficient (0.3%) and those who were no longer deficient after supplementation (1.7%;
conclusionThe results of this research suggest that the vitamin D status at time of fracture affects fracture healing. Further research is needed to confirm these results.
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