ArticleScience (New York, N.Y.)2017
Breathing control center neurons that promote arousal in mice.
Article in Science (New York, N.Y.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 144 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
144 citing papers in PubMed, 2 syntheses or guidelines pooled it, 293 citations in OpenAlex.
- Effects of traditional Chinese mind-body exercise-Baduanjin for type 2 diabetes on psychological well-being: A systematic review and meta-analysis.Frontiers in public health · 2022Pooled it
- Mindfulness-Based Baduanjin Exercise for Depression and Anxiety in People with Physical or Mental Illnesses: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2018Pooled it
- The Effect of 4-7-8 Breathing Exercise Technique on Tinnitus Handicap, Psychological Factors, and Sleep Quality in Tinnitus Patients: A Randomized Controlled Study.Brain and behavior · 2026Trial
- A Randomized Clinical Trial Reveals Effects of Mindfulness and Slow Breathing on Plasma Amyloid Beta Levels.Psychophysiology · 2025Trial
- Effect of Baduanjin exercise on health and functional status in patients with chronic obstructive pulmonary disease: a community-based, cluster-randomized controlled trial.NPJ primary care respiratory medicine · 2024Trial
- Daily heart rate variability biofeedback training decreases locus coeruleus MRI contrast in younger adults in a randomized clinical trial.International journal of psychophysiology : official journal of the International Organization of Psychophysiology · 2023Trial
- Brief structured respiration practices enhance mood and reduce physiological arousal.Cell reports. Medicine · 2023Trial
- Insular routing to orbitofrontal cortex enables breathing awareness.Science advances · 2026Article
- Article
- Spontaneous perceptual reversals are accompanied by systematic changes in pupil size but not respiration phase.Scientific reports · 2026Article
- Respiratory pauses highlight sleep architecture in mice.Nature communications · 2026Article
- Vagal nerve TRPV3 regulates sedative-mediated appeasement.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Respiration as a dynamic modulator of sensory sampling.Nature communications · 2026Article
- Respiratory-Limbic Coupling via a Thalamic Circuit Alleviates Anxiety.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Neural signatures of human psychological resilience driven by acute stress.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Phonation-Based Spiritual Practices and Autonomic Regulation: A Systematic Review and Meta-Analysis Testing the S-CN Model.Applied psychophysiology and biofeedback · 2026Article
- Daily Paced Breathing Sessions Induce Left Orbitofrontal Volume Changes Linked to Cognitive Outcomes.medRxiv : the preprint server for health sciences · 2026Article
- How breathing disrupts vision: hyperventilation-induced hypocapnia impairs oculomotor responses in resting humans.The Journal of physiology · 2026Article
- Wakefulness regulation of memory encoding and retrieval: structure and activity.National science review · 2026Review
- Respiration Shapes the Neural Dynamics of Successful Remembering in Humans.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
84 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
Slow, controlled breathing has been used for centuries to promote mental calming, and it is used clinically to suppress excessive arousal such as panic attacks. However, the physiological and neural basis of the relationship between breathing and higher-order brain activity is unknown. We found a neuronal subpopulation in the mouse preBötzinger complex (preBötC), the primary breathing rhythm generator, which regulates the balance between calm and arousal behaviors. Conditional, bilateral genetic ablation of the ~175
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.