ArticleTobacco control2018
Preliminary evidence that high levels of nicotine on children's hands may contribute to overall tobacco smoke exposure.
Article in Tobacco control, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02531594 (An Intervention to Reduce Second Hand Smoke Exposure Among Pediatric Emergency Patients), which is not on this map. Cited by 37 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
An Intervention to Reduce Second Hand Smoke Exposure Among Pediatric Emergency Patients
Who cites it
37 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.
- Analysis of Assessment Methods for Detecting Nicotine Residue and Its Impact on Humans: A Systematic Review.International journal of environmental research and public health · 2025Pooled it
- Sex-specific modulation of lung function and transcriptome in neonate mice exposed to thirdhand electronic-cigarette aerosols.Pediatric research · 2026Article
- Assessment, detection, and validation of clinical associations of thirdhand smoke exposure (ADVOCATE) study protocol.Pediatric research · 2025Article
- Assessing parental awareness and concerns about children's tobacco smoke exposure: a community-based analysis.Archives of public health = Archives belges de sante publique · 2025Article
- Secondhand smoke exposure and behavioral problems in Japanese schoolchildren.Frontiers in public health · 2025Article
- Cotton pillow samplers for assessment of thirdhand smoke in homes of smokers and nonsmokers with children.Journal of environmental exposure assessment · 2024Article
- Exposure to Secondhand Smoke Extract Increases Cisplatin Resistance in Head and Neck Cancer Cells.International journal of molecular sciences · 2024Article
- Secondhand tobacco smoke exposure in homes and vehicles in youth: disparities among racial, and sexual and gender minorities.Frontiers in public health · 2024Article
- Article
- Pre- and postnatal exposure to secondhand tobacco smoke and cardiometabolic risk at 12 years: Periods of susceptibility.Environmental research · 2023Article
- Distinguishing Exposure to Secondhand and Thirdhand Tobacco Smoke among U.S. Children Using Machine Learning: NHANES 2013-2016.Environmental science & technology · 2023Article
- Hand nicotine as an independent marker of thirdhand smoke pollution in children's environments.The Science of the total environment · 2022Article
- Barriers to implementation of pediatric emergency department interventions for parental tobacco use and dependence: a qualitative study using the theoretical domains framework.Implementation science communications · 2022Article
- Differential associations of hand nicotine and urinary cotinine with children's exposure to tobacco smoke and clinical outcomes.Environmental research · 2021Article
- Hand Nicotine and Cotinine In Children Exposed to Cigars: A Pilot Study.Tobacco regulatory science · 2021Article
- Comment regarding categorization of Third-hand smoke exposure in "Third-hand Exposure at Homes: Assessment Using Salivary Cotinine".Environmental research · 2021Article
- Collecting Hand Wipe Samples to Assess Thirdhand Smoke Exposure.Frontiers in public health · 2021Article
- Child tobacco smoke exposure and healthcare resource utilization patterns.Pediatric research · 2020Article
- Persistent tobacco smoke residue in multiunit housing: Legacy of permissive indoor smoking policies and challenges in the implementation of smoking bans.Preventive medicine reports · 2020Article
- Letter to the Editor Regarding: "An Imperative Need for Research on the Role of Environmental Factors in Transmission of Novel Coronavirus (COVID-19)" -Secondhand and Thirdhand Smoke As Potential Sources of COVID-19.Environmental science & technology · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundDust and surfaces are important sources of lead and pesticide exposure in young children. The purpose of this pilot study was to investigate if third-hand smoke (THS) pollutants accumulate on the hands of children who live in environments where tobacco is used and if hand nicotine levels are associated with second-hand smoke (SHS), as measured by salivary cotinine.
methodsParticipants were parents and children (n=25; age mean (SD)=5.4 (5.3) years) presenting to the emergency department with a potentially SHS-related illness. A convenience sample of participants were recruited at baseline from an ongoing two-group, randomised controlled trial of a SHS reduction and tobacco cessation intervention. Parents were current smokers; thus, all children were at risk of SHS and THS exposure to varying extents. Primary outcome measures, which were assessed in child participants only, were hand nicotine and salivary cotinine. Parents reported sociodemographics and smoking patterns; children's medical records were abstracted for chief complaint, medical history and discharge diagnosis.
resultsAll children had detectable hand nicotine (range=18.3-690.9 ng/wipe). All but one had detectable cotinine (range=1.2-28.8 ng/mL). Multiple linear regression results showed a significant positive association between hand nicotine and cotinine (p=0.009; semipartial r DISCUSSION: The higher-than-expected nicotine levels and significant association with cotinine indicate that THS may play a role in the overall exposure of young children to tobacco smoke toxicants and that hand wipes could be a useful marker of overall tobacco smoke pollution and a proxy for exposure. TRIAL REGISTRATION NUMBER: ClinicalTrials.gov Identifier: NCT02531594.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.