Evidence map›Paper›PMID 28359643›Full record

ReviewJournal of voice : official journal of the Voice Foundation2017

Insights Into the Role of Collagen in Vocal Fold Health and Disease.

Sharon S Tang, Vidisha Mohad, Madhu Gowda, Susan L Thibeault

Abstract readReview
In one paragraph

Review in Journal of voice : official journal of the Voice Foundation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Efficacy of platelet-rich plasma (PRP) in benign vocal fold lesions: a systematic review and meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024
    Pooled it
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  20. Hydrogel-Supported, Engineered Model of Vocal Fold Epithelium.ACS biomaterials science & engineering · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sharon S TangDepartment of Communication Sciences and Disorders, Department of Surgery, Division of Otolaryngology-Head & Neck Surgery, University of Wisconsin-Madison, Madison, Wisconsin.
Vidisha MohadDepartment of Communication Sciences and Disorders, Department of Surgery, Division of Otolaryngology-Head & Neck Surgery, University of Wisconsin-Madison, Madison, Wisconsin.
Madhu GowdaDepartment of Surgery, Division of Otolaryngology-Head & Neck Surgery, University of Wisconsin-Madison, Madison, Wisconsin.
Susan L ThibeaultDepartment of Surgery, Voice and Swallow Clinics, Division of Otolaryngology-Head & Neck Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin. Electronic address: thibeault@surgery.wisc.edu.

Funding

Engineering the Vocal Fold MucosaR01DC004336 · NIDCD · UNIVERSITY OF WISCONSIN-MADISON · PI Susan Lynn Thibeault · 2000 to 2026
$14.6M
University of Wisconsin Voice Research Training Program (T32)T32DC009401 · NIDCD · UNIVERSITY OF WISCONSIN-MADISON · PI Susan Lynn Thibeault · 2009 to 2026
$6.3M
Mechanisms of innate immune-microbial interactions in vocal fold InflammationR01DC012773 · NIDCD · UNIVERSITY OF WISCONSIN-MADISON · PI THIBEAULT, SUSAN LYNN · 2013 to 2022
$4.5M
Macrophage And Fibroblast Modulation Toward Chronic Vocal Fold Scar RestorationR01DC013508 · NIDCD · UNIVERSITY OF WISCONSIN-MADISON · PI HAHN, MARIAH S, THIBEAULT, SUSAN LYNN · 2014 to 2018
$2.5M
NIDCD NIH HHS R01 DC004336NIDCD NIH HHS R01 DC012773NIDCD NIH HHS R01 DC013508NIDCD NIH HHS T32 DC009401
6 · The paper itself

Abstract

As one of the key fibrous proteins in the extracellular matrix, collagen plays a significant role in the structural and biomechanical characteristics of the vocal fold. Anchored fibrils of collagen create secure structural regions within the vocal folds and are strong enough to sustain vibratory impact and stretch during phonation. This contributes tensile strength, density, and organization to the vocal folds and influences health and pathogenesis. This review offers a comprehensive summary for a current understanding of collagen within normal vocal fold tissues throughout the life span as well as vocal pathology and wound repair. Further, collagen's molecular structure and biosynthesis are discussed. Finally, collagen alterations in tissue injury and repair and the incorporation of collagen-based biomaterials as a method of treating voice disorders are reviewed.

Indexed as

PhonationVoice QualityAge FactorsAgingBiomechanical PhenomenaCollagenHumansProtein ConformationStructure-Activity RelationshipTensile StrengthVibrationVocal CordsVoice DisordersWound HealingCollagenBiomaterialBiomechanicsCollagenVocal foldWound healing

Identifiers

PMID28359643
PMCPMC5583023

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.